Early Measurement of insulin insensitivity and detection of early pre-diabetics by non invasive measurement of calciuria
Insulin insensitivity has been shown to occur long before it can be observed using a Glucose Tolerance Test, Fasting blood sugar test or the Glycated hemoglobin (A1C) test. This is because very eraly pre-diabetics can maintain noraml blood glucose levels by producing higher than noraml serum insulin levels. Such individuals can be identified in their early twenties. The standard measurement of insulin levels using the "hyperinsulinemic euglycemic clamp" is invasive and invoves blood sample and intravenus infusion of glucose solutions. It requires highly skilled operators and is very expensive.
This invention is a simple means of measuring insulinemia and is simple to adminsiter. It make it possible to detect pre-diabetic individuals (pre-pre-diabetics) much earlier than any existing technique. It involves measurent of urinary calcium following two meals containing exact amounts of noraml food components. One meal contains a high protein level and the other cntaining a noral proten level. The meals are consumed under standard conditions after overnight fasting and on two consecutive days.
Attached files:Patent details 2017201342.docPatents:
AU 2,017,201,342 issued 2017-02-28 [MORE INFO
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