Concentration and Selectivity of Nucleic Acids using a Nano needle

Introduction There is a need in the medical industry for cost-effective, non-invasive methods of sampling biological fluids that often contain bio-markers such as nucleic acids, which can be indicative of disease states; thus, sensitive and specific diagnostic tests to locate bio-markers are needed. Technology description Researchers at the University of Washington have developed highly sensitive and specific method of sampling nucleic acids in peripheral blood using a high aspect ratio nano-needle. The needle is made from hybrid nano-material and in combination with dielectrophoresis and capillary action, it can transfer nucleic acids to a specific spatial location. This method has the capability to be automated in high-throughput form and is a cost-effective, non-invasive alternative to diagnostic approaches that are often highly invasive (e.g. surgery) and expensive. Business opportunity The global market for nanotechnology is approximately $10 billion with projections of over $25 billion by 2011 with annual growth of approximately 19%. The nanoneedle method will enable simple, cost effective, rapid yet reliable sampling of nucleic acids in large, complex mixtures such as bodily fluids. Stage of development Initial data and working prototypes exist for this technology. Intellectual property position The technology is available for licensing. The UW is currently reviewing this technology for worldwide patent protection.

Type of Offer: Licensing



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