Biochemical Sensor in Open Nanochannel

Introduction Micro and nano-sized biochips are convenient for exploring molecular interactions because of their small feature size. The small size of the chips allows for sensitive detection on the molecular level while reducing testing time and sample volumes. Technology description Researchers at the University of Washington have developed a biochemical sensor that uses an array of open nanochannels (10 – 1000nm) to study molecules such as DNA. Channels are fabricated by nanomachining or shadow edge lithography. Due to the open channel design, the biochip allows for easy access to the channels and for the use of light microscopy. Furthermore, large DNA molecules are often more difficult to study in closed channels; thus, the higher degree of freedom in open channels is advantageous when studying these molecules. Business opportunity The biochemical sensor in an open nanochannel represents a breakthrough due to the reduced feature sizes from current microfabricated biochips. This reduces sample amounts needed and processing time while increasing sensitivity and specificity with ultrahigh throughput all at a lower cost than typical biochips. The US biochip market is expected to grow at an annual rate of ~20% through 2008. Stage of development Initial data and a working prototype exist for this technology. Intellectual property position The technology is available for licensing. The UW is currently reviewing this technology for worldwide patent protection.

Type of Offer: Licensing

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