PEO Coated IOL

Introduction Intraocular lenses (IOL) are well established in the area of ophthalmology, and are often used to replace a natural lens affected by cataracts or to compensate for refractive errors. IOL implantation is considered to be surgically advantageous, particularly in the treatment of cataracts. However, this procedure does come with complications, including damage to the corneal endothelium and inflammatory responses within the anterior or posterior segment of the eye. The described invention depicts a coated intraocular lens with an improved biocompatibility, resulting in fewer complications. Technology description This invention relates to an intraocular lens with improved biocompatibility; it is coated with polyethylene oxide through covalent binding, using a plasma-deposited amine layer. The lens is subsequently sterilized with ethylene oxide and extracted with water. This invention is applicable to all lens styles. The biocompatibility of lenses is greatly improved when coated with polyethylene coating, and according to this invention, improves the resistance to protein adsorption. This results in a lens which is “non-fouling” and resistant to cell deposition, thus, more biocompatible than known lenses. Business opportunity There were approximately 2.8 million IOL procedures in the US in 2005 for cataract patients over the age of 72 years. This number is expected to grow at 3% annually. Further, there is potential to expand this market to younger patients with presbyopia. As such, there is a great market opportunity for a coated intraocular lens with improved biocompatibility.

US 5,618,316

Type of Offer: Licensing

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