A Microfluidic Device and Methodology for Rapid, Quantitative Determination of Analyte Concentration in a Fluid Sample

Introduction Advances in microfluidic technology are constantly opening doors to new and exciting applications, especially for biosensors and environmental monitoring. One recent area of interest is point-of-care diagnostic devices. These devices provide fast, accurate, and inexpensive sample analysis. Recent advances have enabled a universal platform that is adaptable to a potentially limitless array of analytes and could lead to affordable health care devices, including for the developing world. Technology Description Researcher Nelson at the University of Washington has developed a single-use, disposable microfluidic device capable of performing rapid, self-calibrating, and quantitative determinations of analyte concentration in liquid samples. By using a selective binding partner, each device can be tailored to a specific analyte for which the dynamics and concentration can be quantitatively monitored by surface plasmon resonance (SPR). The device is currently optimized as a biosensor, using a modified immunoassay, and appropriate samples include blood and saliva; however, the device could be adapted for environmental sensing. Business Opportunity Effective microfluidic assays that are robust and quantitative present opportunities for point-of-care testing for therapeutic drug monitoring, diagnostic testing, and epidemiological studies, realizing significant decreases in time and money spent while improving convenience and patient health. Additional opportunities arise in environmental monitoring. Stage of Development A working prototype of the device has been developed. Intellectual Property Position The UW has patents pending on this technology. For more information on this technology contact:
Kelly FitzGerald, PhD Technology Manager, Invention Licensing [email protected] 206-543-3970

Type of Offer: Licensing

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