Needle Probe for Single and Two-Photon Determination of Human Retinal Health
Introduction Laser imaging of the retina is a well-developed field that has generated state-of-theart scanning laser ophthalmoscopes (SLOs). Autofluorescent materials have been developed that can image the structure of the retina, but are only activated at ultraviolet (UV) wavelengths (200-400 nm). Because the lens of a human eye only transmits visible and near infrared light (700-1500 nm), illuminating the retina with UV is difficult at best. Technology description Researchers at the UW have developed a minimally-invasive approach for imaging the human retina. By auto fluorescence imaging the structure of retinal ester storage particles (RESTs) or the auto fluorescence signal recovery after photobleaching, the retinal health of the subject’s macular region may be determined earlier than any other ophthalmologic procedure available at this time. Business opportunity There are few pharmacological alternatives for the millions of people who suffer from macular degeneration. This method can be used during the development of new pharmaceutical therapies and, eventually, at an ophthalmology clinic for disease diagnosis and monitoring response to trial drug treatments. Stage of development Initial data exist for this technology. Intellectual property position This technology is available for licensing. The UW is currently reviewing this technology for worldwide patent protection.Type of Offer: Licensing
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