Detection of Porphyromonas Gingivalis
This invention is an accurate and sensitive system to detect the presence of Porphyromonas gingivalis, a bacterial strain associated with the development of periodontal disease. The bacteria are detected by identifying the presence of DNA specific t o the strain. This is accomplished via the polymerase chain reaction, a method commonly used to characterize DNA evidence in criminal trials as well as diagnosis of various other disease states. The system includes DNA primers for the polymerase ch ain reaction which are specific for the Porphyromas gingivalis bacteria. This invention can be used as a diagnostic tool to confirm the presence of P. gingivalis in the oral cavity at concentrations three-fold lower than that of current technologies . The early detection and eradication of these bacteria before disease sets in is of significant prophylactic value. This technology has applications in research and diagnosis and can be modified to detect other forms of bacteria that cause periodo ntal disease.
Categories: Diagnostic, Dentistry Patents Issues: 5,432,055
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