�whmd�: Essential Cell Division Gene in Mycobacteria

The slow growth rate of mycobacteria contributes significantly to the pathogenes 'is and treatment of mycobacterial infections such as tuberculosis. To combat infection, patients must undergo extended therapeutic programs that result in poor patient compliance and the emergence of drug-resistant organisms. Little is known about the regulation of mycobacterial cell division; however, understanding of the mechanisms underlying the growth of these organisms may lead to new methods for the diagnosis and treatment of mycobacterial disease. This technology provides for the identification and characterization of a gene family essential to cell division via the regulation of sporulation in mycobacteria. Description (Set) Proposed Use (Set) This technology provides for genes and corresponding proteins that may be used to identify and develop new agents for the diagnosis and treatment of mycobacterial infections such as tuberculosis, Mycobacterium avium complex (MAC) infection, leprosy, and atypical mycobacterial infections.

Patent (Set) 6,590,087

Patents:
US 6,590,087

Inventor(s): Bishai, William R.

Type of Offer: Licensing



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