TC-1 (Po)

This cell line "was developed to circumvent the confounding issue of negatively selecting nonessential tumor markers in cancer vaccine experiments. Primary lung epithelial cells from C57BL/6 mice were immortalized with HPV-16 E6 and E7 and then transformed with the activated ras oncogene. This transformation process mimics the natural sequence in the pathogenesis of cervical cancer in which HPV-16 plays a critical role in carcinogenesis". Description (Set) Proposed Use (Set) TC-1 (Po) cell line may be used as a disease model for cervical cancer

Inventor(s): Wu, T.C.

Type of Offer: Licensing



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