A Visual Color Detection System to Identify Agents that Induce Mitochondrial Dysfunction.

Mitochondrial dysfunction can lead to many diseases and can effect any organ at any age. The number of diseases associated with mitochondrial dysfunction has grown tremendously within the past decade and include common maladies as diverse as cancer, diabetes, heart disease, blindness, deafness, kidney disease, liver disease, stroke, infertility and the toxicity due to the treatment of AIDS. Even the aging process and aging associated diseases such as Alzheimer and Parkinson Diseases have been linked to mitochondrial dysfunction. Unfortunately, little is known of the agents responsible for mitochondrial dysfunction. A bioassy has now been developed which can be used to identify the agents or toxins responsible for mitochondrial dysfunction. Description (Set) Proposed Use (Set) Diagnostic Test Methods for Mitochondrial Dysfunction. This bioassay system may be used by toxicologists to determine the potential genetic hazards to mitochondrial DNA and mitochondria from exposure to a variety of suspected agents including known chemical and physical mutagens, newly synthesized chemicals, drugs used in the treatment of cancer

Patent (Set) 6,479,251; WO 01/21758

Patents:
US 6,479,251

Inventor(s): Singh, Keshav K.

Type of Offer: Licensing



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