LOI of lgf2 Increases Intestinal Stem Cell Compartment and Adenoma Formation

This invention provides a strategy for identifying patients at risk of colorectal cancer, and likely other tumor types, by the discovery and identification of an expanded stem cell population in such patients, as well as methods for its detection. Description (Set) Proposed Use (Set) Rapid test for cancer risk detection, e.g., rectal ?Pap?-type test, followed by immunostaining or nucleic acid analysis for risk assessment. Development of products designed to assess ?stem cell expansion? as a measure of cancer risk and precancerous lesions. This technology may lead to an approach in cancer prevention similar to the role of lipid testing in cardiovascular disease prevention. It should also lead to new chemo prevention approaches. Patent (Set) WO2005/18878

Inventor(s): Feinberg, Andrew Paul

Type of Offer: Licensing

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