Malaria Diagnosis in Urine

Scientists at JHU have developed a urine test for malaria, the first of its kind. The test will detect aldolase and pfhistidine-rich protein using an immunoassay design. The infectious agent, Plasmodium falciparum, may also be detected using PCR methodologies. Description (Set) Proposed Use (Set) Each year more than 300 million people suffer from malaria, the majority are from Africa, where the transmission rates approach 90%. Malaria tests are scarce in the neediest populations, and where available, are incorrect over half of the time. Additionally, in endemic areas, a lack of sanitation and clean gloves, the reuse of needles and lack of proper needle disposal increases the transmission of blood borne pathogens such as HIV, hepatitis and even malaria. A urine based dipstick assay will overcome the shortcomings of needle based tests and could be performed in a home based setting rather than in the clinic. In the developed world, the demand for needleless tests is high in worldwide travelers and overseas military.

Inventor(s): Sullivan, David

Type of Offer: Licensing

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