Cell Lines with Targeted Deletions of p53

Abstract (Set) Cell lines with deletions of p53 can be used for testing the specificity of drugs that target the p53 pathway. This pathway is inactivated in multiple forms of tumors. The cells lines include the following: ? HCT116 R248W/- ? DLD1 R248W ? DLD1 -/- ? RKO -/- ? SW48 -/-

Inventor(s): Vogelstein, Bert ,Bunz, Fred ,Kinzler, Kenneth ,Pagliarini, Ray ,Papadopoulos, Nickolas

Type of Offer: Licensing

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