Monoclonal Antibody DZ-1 for M. leprae (leprosy bacillus)

Description The DZ-1 monoclonal antibody detects specific antigen for the leprosy bacillus, Mycobacterium leprae. The recognized antigen is Phenolicglycolipid-I (PG-I). The monoclonal antibody reacts with the innermost sugar (0-3-methylrhamnose) of the trisaccharide antigenic component of the PG-I. Applications Leprosy, also known as Hansen's disease, is an infectious disease commonly manifested by cutaneous and neural lesions. The antibody response of the DZ-1 monoclonal antibody to the PG-I antigen is highly specific and has been shown to detect the leprosy-associated antigen PG-I in blood/serum, nasal secretions, tissues and urine. It could be used in a leprosy diagnostic test kit and also to monitor treatment progress. Main Advantages Higher sensitivity to PG-I than other known monoclonal antibodies. Very high titers or concentration is produced in ascites fluid.

Type of Offer: Licensing

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