Image Guided Interstitial Ultrasound Therapy

The Technology

The probe’s delivery system includes five independent channels, each capable of producing up to 50W of RF power. An MRI-compatible motor has also been developed to control the rotation of the heating applicator inside the bore of a clinical 1.5T MR scanner. The capability to perform real-time quantitative thermometry and control during heating with these applicators has been demonstrated with MRI. Initial in-vivo trials show very promising results.

The Challenge Clinicians have long sought a reliable and controllable means of accurately delivering thermal therapy to internal tumors and organs with a treatment that has maximum effect on the target and minimal effect on surrounding tissues. The Opportunity Partners required to license and/or invest in Image Guided Interstitial 3D Ultrasound therapy, for launch in to commercially significant, high-value, high-margin markets:
• Prostate Cancer (3rd leading cause of cancer in men)
• Enlarged Prostate (affects majority of men)
• Catheter based thermal therapy of other cancerous or benign tumors The Solution Image Guided Interstitial 3D Ultrasound therapy, developed by Sunnybrook Hospital researchers, employs a uniquely versatile and controllable interstitial probe to perform ultrasound thermal therapy under MRI guidance. Ultrasound energy is delivered from a rotating multi-element heating applicator incorporating multi-frequency transducers. The heating applicator produces a directional heating pattern and has the capability to generate complex three dimensional thermal damage patterns in tissue. MRI guidance gives excellent real-time control of probe position and heating pattern as well as monitoring the therapy’s effect on the tissue. The technology is compatible with other imaging methods such as CT and Ultrasound. The Technology The probe’s delivery system includes five independent channels, each capable of producing up to 50W of RF power. An MRI-compatible motor has also been developed to control the rotation of the heating applicator inside the bore of a clinical 1.5T MR scanner. The capability to perform real-time quantitative thermometry and control during heating with these applicators has been demonstrated with MRI. Initial in-vivo trials show very promising results. Patent Status US6589174. US20060206105.

Patents:
US 6,589,174
US 20,060,206,105

Type of Offer: Licensing



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