Organic-inorganic Hybrid Nano Particle Composed of Nucleic Acid Conjugate Having Polyethylene Glycol Bound Thereto and Calcium Phosphate
Disclosed is an organic-inorganic hybrid nano particle comprising a conjugate of a nucleic acid and a polyethylene glycol chain bound covalently to the nucleic acid and a calcium ion (Ca2+) and a phosphate ion (PO4 3-). The particle can be used as an effective delivery system for delivering a nucleic acid into a cell.
KATAOKA KAZUNORI; ZHANG MINGZHEN; ISHII ATSUSHI; NISHIYAMA NOBUHIRO; MATSUMOTO SATORU
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