Anti-inflammatory and Wound Healing Effects of Lymphoid Thymosin B-4

The invention relates to a method of treating inflammatory conditions in a subject comprising administering to a subject a composition comprising a lymphoid thymosin-beta4 polypeptide or a functional lymphoid thymosin-beta4 polypeptide variant. The invention also provides a method of promoting wound healing in a subject comprising administering to the subject a composition comprising a lymphoid thymosin-beta4 polypeptide or a functional lymphoid thymosin-beta4 polypeptide variant. The invention also relates to methods of treating the above mentioned conditions in a subject comprising administering to the subject a nucleic acid encoding a lymphoid thymosin-beta4 polypeptide or a functional lymphoid thymosin-beta4 polypeptide variant. The invention also relates to pharmaceutical compositions comprising a lymphoid thymosin-beta4 polypeptide or a functional lymphoid thymosin-beta4 polypeptide variant, or salt thereof, and a pharmaceutically acceptable carrier.

Patents:
US 20,090,317,457

Inventor(s): GIRARDI MICHAEL [US]; TIGELAAR ROBERT E [US]; SHERLING MICHAEL A [US]; SHIRES JOHN [US]; HAYDAY ADRIAN C [GB]; THEODORIDIS EFSTA

Type of Offer: Sale



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