Xenobiotic Related Induction of Gene Expression

An isolated nucleic acid molecule comprising a nucleotide sequence encoding a transcriptional enhancer of cytochrome P450 (P450) CYP3A4 production or expression, and uses of the nucleic acid molecule for screening compounds for xenobiotic induction of CYP3A4 expression in cells and animals.

Patents:
US 20,100,146,652

Inventor(s): LIDDLE CHRISTOPHER [AU]; GOODWIN BRYAN JAMES [US]

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