Methods, compositions and kits for vegetative cell-based vaccines and spore-based vaccines

Methods for immunizing a subject to an antigen of an infectious agent, a tumor, or an allergen are provided, using vegetative cytoplasmic expression of the antigen or spore surface display of the antigen, and contacting the subject with a composition including a spore or a vegetative cell or both with or without an adjuvant. Also included are thermally-stable vaccine compositions using the method described above and kits including the compositions.

Patents:
US 20,110,104,200

Inventor(s): HERRMANN JOHN E [US]; BELITSKY BORIS R [US]; SONENSHEIN ABRAHAM L [US]; TZIPORI SAUL [US]

Type of Offer: Licensing



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