Method for Selectively Inhibiting the Activity of Acat1 in the Treatment of Alzheimer's Disease

The present invention features methods for decreasing the size and density of amyloid plaques, decreasing cognitive decline associated with amyloid pathology, and treating Alzheimer's disease by selectively inhibiting the activity of Acyl -CoA: Cholesterol Acyltransferase 1, but not Acyl -CoA: Cholesterol Acyltransferase 2.

Patents:
WO 2,010,042,292

Inventor(s): CHANG TA-YUAN [US]; CHANG CATHERINE C Y [US]

Type of Offer: Licensing



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