Nontoxic Shiga-like Toxin Mutant Compositions and Methods

Disclosed are nontoxic mutants of Shiga-like toxin (Stx1 or Stx2), nucleic acids encoding them, compositions containing the mutants and methods of using the mutants in connection with hemolytic euremic syndrome (HUS). Also disclosed are methods of treating HUS using L3 protein fragments, the nontoxic Stx1 or Stx2 mutants, or combinations thereof.

WO 2,009,088,403

Inventor(s): TUMER NILGUN E [US]; DI RONG [US]

Type of Offer: Licensing

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