Lysine-specific Demethylase Inhibitors

Polyamine, polyamine/guanidino, and polyamine/biguanide compounds bearing allene, propargyl, cyclopropyl, and other reactive moieties are disclosed. The compounds are useful as irreversible inhibitors of the enzyme lysine-specific demethylase-1 and for the treatment of cancer.

Patents:
US 20,110,092,601

Inventor(s): WOSTER PATRICK M [US]; CASERO ROBERT A [US]

Type of Offer: Licensing



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