Methods of Diagnosing and Treating Fibrosis

The present invention is directed to methods of diagnosing and treating a fibrotic condition in a mammalian subject. These methods involve measuring the levels of trimethylation at lysine residue 27 of histone-3 and/or measuring the expression levels of EZH2 or YY-1. Agents useful for treating fibrosis or a fibrotic condition are also disclosed.

Patents:
WO 2,010,051,550

Inventor(s): GUO JIA [US]; LIN XIN [US]; GEORAS STEVE [US]; SIME PATRICIA [US]

Type of Offer: Licensing



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