Use of Biliverdin Reductase (bvr) and Bvr Peptide Fragments to Treat Coronary Disorders

The present invention relates to methods and compositions for treating coronary disorders and preventing cardiac cell death that involve the use of biliverdin reductase ("BVR") or BVR peptides to stabilize the expression and activity of intracellular HO-2 in cardiac cells. The present invention also relates to methods and compositions for inducing cancer cell death in a patient having cancer that involve the use of inhibitory BVR peptides to destabilize intracellular HO-2 expression and activity, thereby augmenting cell death.

Patents:
US 20,100,303,790

Inventor(s): MAINES MAHIN D [US]

Type of Offer: Licensing



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