Methods of Diagnosing, Preventing and Treating Bone Mass Diseases

The present invention provides methods and therapeutic agents for lowering or increasing serum serotonin levels in a patient in order to increase or decrease bone mass, respectively. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis and the agents are TPHl inhibitors or serotonin receptor antagonists.

Patents:
KR 20,110,008,066

Inventor(s): KARSENTY GERARD [US]; DUCY PATRICIA F [US]; XIE YULI [CN]; LANDRY DONALD [US]; YADAV VIJAY [IN]

Type of Offer: Licensing



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