Use of RNA for Reprogramming Somatic Cells
The present invention provides methods for de-differentiating somatic cells into stem-like cells without generating embryos or fetuses. More specifically,-the present invention provides methods for effecting the de-differentiation of somatic cells to cells having stem cell characteristics, in particular pluripotency, by introducing RNA encoding factors inducing the de-differentiation of somatic cells into the somatic cells and culturing the somatic cells allowing the cells to de-differentiate.
EP 2,240,572 [MORE INFO
SAHIN UGUR [DE]; POLEGANOV MARCO [DE]; BEISSERT TIM [DE]
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