Reatment of Suicidal Ideation Or Behavior Using Inhibitors of Nicotinic Acetylcholine Receptors

The invention concerns methods of treating suicidal ideation or behavior in a subject in need thereof, comprising decreasing endogenous nicotinic acetylcholine receptor (nAChR) activity in the subject; therapeutic packages for treating suicidal ideation or behavior; and methods for determining the efficacy of a treatment for suicidal ideation or behavior. In some embodiments, the treatment methods comprise administering to the subject an effective amount of an inhibitor of a nAChR, such as a lithium compound, mecamylamine, clozapine, or asenapine.

Patents:
US 9,180,191 issued 2015-11-10   [MORE INFO]

Inventor(s): SHEEHAN DAVID V [US]; SHYTLE R DOUGLAS [US]

Type of Offer: Licensing



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