Tome-1, a novel cell-cycle gene required for mitotic entry

Summary This invention, out of Marc Kirschner's research group, concerns the discovery of a novel protein required for mititic entry. Harvard researchers have isolated and identified the protein and the gene encoding the protein. Further work has shown Tome-1's key role in the activation of cdk1/Cyclin B, in turn required for mitotic entry.

Further details are available in Cell, Vol. 113, 1-20, April 4, 2003

Applications antimitotic antiproliferative oncology autoimmune For Further Information Please Contact the Director of Business Development Michal Preminger Email: michal_preminger@hms.harvard.edu Telephone: (617) 432-0920

Inventor(s): Kirschner, Marc W

Type of Offer: Licensing



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