Novel Clinical Stage Treatments for Epilepsy and Pain

Summary The principal investigator has discovered that Huperzine A (HupA) is characterized by extremely potent therapeutic activity against epilepsy and chronic pain. HupA was tested in a formalin model of pain, in which it produced complete inhibition of pain behavior in all treated mice, with a dosage well below known TD50 values. HupA has also shown extensive evidence for being effective in various animal models of epilepsy, including the 6-Hz mouse model.

Clinical studies are being pursued in 2007.

Applications The markets being pursued are epilepsy, where despite a number of effective drugs on the market there remains a large unmet medical need, and pain (both chronic and acute), another large market need. For Further Information Please Contact the Director of Business Development Katie Gordon Email: Telephone: (617) 432-0920

Inventor(s): Schachter, Steven C.

Type of Offer: Licensing

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