DEC1 KO Lines for Drug Discovery

Deleted in esophageal cancer 1 (DEC1) gene knockouts of the human keratinocyte cell line, HaCaT. Details are described in the paper by Zawel et al., 2002 Description (Set) Proposed Use (Set) The cell lines described in this invention can be used in screens for novel molecules that target the TGF-Beta pathway in human cancer cells or to confirm the specificity of drugs discovered through other approaches. Such drugs can potentially be used as chemotherapeutic or chemopreventive agents.

Inventor(s): Vogelstein, Bert

Type of Offer: Licensing

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