XIAP KO Lines for Drug Discovery

X-linked inhibitor of apoptosis protein (XIAP) gene knockouts of human colon cancer cell lines. Details are described in the paper by Cummins et al., 2004 (see below). Description (Set) Proposed Use (Set) The cell lines described in this invention can be used in screens for novel molecules that target the mitochondrial death pathway in human cancer cells or to confirm the specificity of drugs discovered through other approaches. Such drugs can potentially be used as chemotherapeutic or chemopreventive agents.

Inventor(s): Vogelstein, Bert

Type of Offer: Licensing

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