Mutational Analysis of the Serine-threonine Kinome in Colorectal Cancers

The invention describes novel mutations in serine-threonine kinase genes within the Phosphatidylinositol-3-OH Kinase (PI(3)K) pathway in patients with colorectal cancer. Details are described in the paper by Parsons et al., 2005 (see below). Description (Set) Proposed Use (Set) The discovery of novel mutations in PI(3)K pathway genes provide a basis for the development of new therapeutic and diagnostic approaches for such patients.

Inventor(s): Vogelstein, Bert

Type of Offer: Licensing

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