293 Cell Line for Flag-tagged HIMF (flag-HIMF-293)

Hypoxia-induced mitogenic factor (HIMF) is highly up regulated in the lungs as a result of hypoxia-induced pulmonary hypertension, and has proangiogenic and proinflammatory effects in the lung. As a research tool for studying the function and activity of HIMF, JHU researchers have developed a transgenic HEK 293 cell line expresses a Flag-tagged HIMF. Expression of the Flag-tagged HIMF protein can be induced by tetracycline and most of the protein is secreted into the culture medium where it can be readily purified by column chromatography. Description (Set) Proposed Use (Set) This cell line model provides an important research tool for studying the function and activity of HIMF.

Inventor(s): Johns, Roger A.

Type of Offer: Licensing



« More Medical Patents

---