Anti-viral Target for Herpes Virus
Abstract (Set) A herpes virus proteinase has been identified and cloned from cytomegalovirus. The substrate for the proteinase, which is an assembly protein precursor, has also been identified. The proteinase is useful in an assay for identifying inhibitors as potential antiviral therapies. Such inhibitors are based upon the structure and sequence of the substrate. Description (Set) Proposed Use (Set) Assay for inhibitors of herpes virus, particularly cytomegalovirus, as potential therapeutic agents.
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