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Photovoltaic Devices
A photovoltaic device including cathode and anode electrodes (3, 11), and a photovoltaically active layer (5) located over both said electrodes
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Radio Frequency Transponder System
A radio frequency transponder, including: a substrate; and at least one planar antenna on said substrate, said antenna having a shape determining a corresponding resonant frequency of said antenna; wherein said antenna causes a phase difference between backscattered signals generated in response to
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Amnion Epithelial Cells for the Treatment of Degenerative Disc Disease
An orthopaedic device and methods for the treatment of degenerative disc disease (DDD) are disclosed that utilise cells such as multipotent amnion epithelial cells (AECs) and/or mesenchymal stem cells (MSCs) that may be directed towards a disc cartilage type cell for the in situ generation of interv
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Contoxin Analogues and Methods for Synthesizing Same
According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.
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Crystal Structure of PfA-M1 and the Pfa-mi Co4 Complex
The invention relates to the X-ray crystal structure of PfA-M1 aminopeptidase alone, and in complex with the phosphinate dipeptide analogue hPheP[CH2]Phe. More specifically the present invention provides the structure coordinates of PfA-M1 and PfA-M1 in complex with Co4. The invention also includes
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Methods of Treating Thromboembolic Disorders
The field of the invention relates to methods for dissolving a thrombus using inhibitors of platelet contractility. More particularly, the present invention relates to the use of an inhibitor of platelet contractility in combination with one or more thrombolytic agents and optionally one or more ant
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Peptide Purification By Means of Metal Ion Affinity Chromatography
PROBLEM TO BE SOLVED: To provide an oligopeptide (tag) for purifying an objective protein and a polymer substrate for metal ion affinity chromatography. ; SOLUTION: The polymer substrate is functionalized with a functionality comprising at least one cyclic, metal ion coordinating ligand group. The c
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Crystal Structure of a Bacterial Enzyme and Uses Thereof
The present invention is predicated, in part, on the determination of the crystal structure of Staphylococcus aureus biotin protein ligase. The present invention provides, among other things, the crystal structure of Staphylococcus aureus biotin protein ligase complexed with biotinyl 5'-adenylate at
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Diagnostic and Therapeutic Protocols
The present invention relates generally to the fields of diagnostic assays and therapeutic protocols with respect to viral infection.
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A1 Adenosine Receptor Allosteric Enhancers
The present invention relates generally to chemical compounds and methods for their use and preparation. In particular, the invention relates to chemical compounds which may possess useful therapeutic activity for treating conditions where the promotion of angiogensis (blood vessel formation) is ben
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Service Value Calculation Method, System, and Program
A service value calculation system includes: crisis problem inspection means which detects a crisis or a problem of a service object; and virtual damage amount calculation means which calculates a virtual damage amount generated if a detected crisis or problem is not solved when a service is not app
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Controlled Polymerisation Process
The present invention relates to a controlled metathesis-driven polymerisation process which is particularly useful for the synthesis of biological polymers such as peptides and polymers. The invention also provides metathesisable supports, groups and linkers for use in the process.
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Time Gated Fluorescent Flow Cytometer
An apparatus (10) for detecting a particle (12) labelled with a fluorescent marker is disclosed. The apparatus (10) has a flow cell (16) being adapted to contain a fluid (14) in which the particle (12) is suspended. A light source (28) is operatively coupled to the flow cell (16) and arranged for em
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Continuous-wave Laser
A continuous wave Raman laser for producing visible laser output comprising: a resonator cavity; at least a first reflector and a second reflector said first and second reflectors being located at opposite ends of the resonator cavity; a laser gain medium located in the resonator cavity for generati
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An Optical Amplifier, a Laser and Methods of Manufacture Thereof
An optical waveguide device (2000) comprising at least one optical waveguide (2002) formed within a bulk optical material (2001), the waveguide having a central longitudinal axis (2004), and a grating formation (2005) within the bulk optical material (2001) co-axial with the axis of at least one opt
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Detection and Quantification of Polypeptides Using Mass Spectrometry
The invention relates to the detection and quantification of polypeptides using mass spectrometry. Specifically, the invention provides a method for testing whether a target polypeptide is present in a sample of a set of polypeptides, a method for deriving a value for distinguishing polypeptides of
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Production of Sea Urchin Roe
A method of producing edible sea urchin roe including the steps, selecting sea urchins having pre-gametogenic gonads, providing a receptacle for cultivation of the selected sea urchins, the receptacle containing seawater and being capable of being provided with (A) a selected temperature and (B) an
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Synthesis of Ageladine a and Analogs Thereof
The invention describes a one pot process for synthesizing a compound of structure (I), or a tautomer thereof. A compound of structure (II), or a tautomer thereof, and an aldehyde of structure RdCHO are condensed to form a condensation product. The resulting condensation product is then oxidized in
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Vessel Support Device and Methods for Supporting a Vessel
The present invention is directed to a vessel support member having opposing ends adapted to move in a circumferential plane, the support member configured for deployment in a substantially radial direction to support a substantial portion of the circumference of a vessel, the support member adapted
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Auto-synchronous Fluorescence Detection Method and Apparatus
An apparatus for time-gated fluorescence or luminescence detection includes gating means (206) arranged to alternately permit light from an excitation source (242) to be directed to a sample (235) along a first communication path (231, 232), and then permit light emitted from the sample to be direct
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Plant Gene Expression
The present invention relates to a nucleic acid molecule for forming a promoter for regulating transcription of a gene in a plant in anoxic conditions including one or more nucleotide sequences as shown in SEQ. ID Nos. 1 - 14 wherein each of the sequences are spaced apart from each other to define r
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Process for the Preparation of Graphene
The present invention relates to a process for the preparation of graphene which can be used in the development of graphene paper or films, graphene-based composites and articles for nanoelectronics, nanocomposites, batteries, supercapacitors, hydrogen storage and bioapplications. This process compr
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Apparatus and Method for Welding
The present invention relates to arc welding torch and a method of extracting fume gas from a welding site. The torch comprises a metal electrode and at least one shield gas port adapted to direct a shield gas curtain around the metal electrode and a welding site. At least one shroud gas port is spa
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Content Based Image Retrieval
A content based image retrieval system that extracts images from a database of images by constructing a query set of features and displaying images that have a minimum dissimilarity metric from images in the database. The dissimilarity metric is a weighted summation of distances between features in
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A New Type of Gapless Semiconductor Material
The present disclosure provides a new type of gapless semiconductor material having electronic properties that can be characterized by an electronic band structure which comprises valence and conduction band portions VB1 and CB1, respectively, for a first electron spin polarisation, and valence and
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Separation and recovery of precious metals using polymer materials.
A method of separation and/or recovery of a precious metal from a solution containing said precious metal in ionic form, optionally in the presence of impurities, including the step of contacting a solution containing said precious metal in ionic form with a conducting polymer. The method is general
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Method of Synthesis of a Superconducting Material
A method of synthesizing a superconducting material, comprising mixing starting materials comprising magnesium, boron, silicon and carbon; heating the mixture of starting materials to a temperature in the range between 650 DEG C. and 2000 DEG C. to produce a material comprising magnesium boride dope
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Polymer electrolytes and devices containing them
The application arises from studies that have shown that electrochemical cells containing SPEs including: (i) a non-volatile organic ionic salt; and (ii) an inorganic electrolyte salt have an improved conductivity across a range of temperatures, and are more stable to water compared to electrochemic
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Dye Composition for Use in Photoelectric Material
A dye composition for use in a photoelectric material, the dye composition comprising a plurality of dyes comprising a chromophore and at least one binding group for binding with a semiconductor (preferably a metal oxide semiconductor) wherein the plurality of dyes include a first dye wherein the bi
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Method and Apparatus
A method of providing cognitive training to a user, the method including, in a processing system, presenting a cognitive task to a user, the cognitive task requiring the user to view presented information and provide at least one input response; determining the at least one input response using an i
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Sports Bra
An encapsulation and compression sports bra (1) with cups (7) formed of elastic material to elevate and compress breasts (8) of a wearer (2) to restrict anatomical breast support structures reaching their end of range during downward breast trajectory to thereby reduce exercise induced breast discom
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Method for the Determination of the Position of Unsaturation in a Compound
A mass spectrometric method for determining the position of unsaturation in a compound is disclosed.
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Prepolymer Composition
The present invention relates to a prepolymer composition comprising a polyester prepolymer, a vinyl-functional monomer having a vapour pressure which is less than styrene at 20 DEG C and an accelerator. The prepolymer composition can be combined with a promoter which causes the prepolymer compositi
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Imaging Method and System
A probe (14; 14'), comprising an ultrasonic probe (56a, 56b; 74a, 74b) and a pixellated radiation detector (16) with discrete detecting elements (50a, 50b, 50c) for detecting a predefined radiation. The probe (14) is adapted to be located at least partially within a body cavity. Also, an imaging met
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Peptoid compounds
The invention relates to new peptoid compounds of formula (I), as well as their use in the treatment of bacterial infections, such as those caused by vancomycin resistant microorganisms, and to compositions thereof.
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Improvements in Magnesium Diboride Superconducting Materials and Methods of Synthesis
Improved magnesium diboride superconducting materials and methods of synthesis are disclosed. Embodiments of the superconducting material comprise at least two starting materials capable of forming MgB2 and at least one dopant compound comprising silicon, carbon, hydrogen and oxygen. The starting ma
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Diagnostics in a Monoplex/multiplex Format
The present invention relates to a method of detecting and/or quantifying a target molecule from a sample obtained from a subject wherein the method comprises: (i) incubating a fusion protein or conjugate comprising a Ter binding polypeptide fused to at least one anti-target molecule or fragment the
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Nanotube and carbon layer nanostructured composites
The present invention relates to nanostructured composites comprising a nanotube network which is at least partially embedded within a carbon layer. The present invention particularly relates to conducting nanostructured composites for use in the fields of energy conversion, energy storage and also
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PDZ Domain Modulators
This invention relates to compounds useful as PDZ domain modulators, in particular the PDZ domain of PICK1. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions.
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Precision Seeders
The invention provides a seed metering mechanism and a method for controlling the seed metering mechanism. The seed metering mechanism includes a seed metering disc (10) that rotates to drop a plurality of seeds in succession. The rotational speed of the seed metering disc (10) between successive se
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Polymer Filaments
The invention relates to polymer filaments and methods for their production. In particular, although not exclusively, the invention relates to conducting polymer filaments and their production from solutions of polymerisable oxidizable monomer units.
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Pasture Management
A plant matter sensor, the sensor includes a pair of parallel spaced apart sensor arms and a control console, a first of the arms having a plurality of emitter means spaced along its length, each emitter configured and arranged to, in use, emit a signal substantially perpendicularly to the arm to be
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Methods for reducing the incidence of mastitis by administration of keratin
Disclosed are methods of reducing the incidence of mastitis, inducing leucycytosis and of sealing a teat canal of a non-human animal such as a cow, including the step of introducing a composition including keratin into the teat canal of the animal, thereby reducing the incidence of mastitis in said
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Lipid Encapsulation
The invention relates to an emulsion for protecting oxidisable lipids from oxidative damage and methods of making the same. The lipids are encapsulated in a complex of casein and whey protein.
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Vaccine
The invention provides a vaccine comprising secreted protein derived from Mycobacterium avium subsp paratuberculosis (M. ptb) substantially free of whole organisms of that species either dead or alive. The secreted protein may be obtained from a culture of M. ptb with the microorganisms being remove
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Membrane Protein Expression System and Its Application in Drug Screening
PROBLEM TO BE SOLVED: To provide a convenient in vitro membrane protein expression system using an inhibitor of drug efflux pump proteins and heterologous cells for testing other drug resistance-relating cell membrane proteins. ; SOLUTION: Provided is a protein expression system comprising an in vit
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Immunogenic polypeptide isolated from mycobacterium avium subspecies paratuberculosis and uses thereof
The present invention relates to an immunogenic polypeptide isolated from Mycobacterium avium subspecies paratuberculosis and variants of the polypeptide. The polypeptide and variants may be used in vaccines against Johne's disease and in methods for detection of the disease. Antibodies against the
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Fusion Polypeptides and Uses Thereof
The invention relates to fusion polypeptides comprising a polynucleotide-binding domain, such as a DNA-binding domain, and a ligase domain, such as a DNA ligase domain, methods for the production of such fusion polypeptides, and uses of the fusion polypeptides, for example in a range of molecular bi
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Novel Assay
The invention relates to a translational recoding reporter construct comprising: a first fluorescent protein coding sequence; a second fluorescent protein coding sequence encoding a fluorescent protein different from the first fluorescent protein; and a linker sequence interposed between the first a
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Method of Identifying Individuals At Risk of Thiopurine Drug Resistance and Intolerance
The present invention is directed to a method of screening individuals for the presence or absence of one or more polymorphisms associated with the risk of thiopurine resistance or intolerance.
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Anti-cancer Compositions Containing a Shark Meat Extract and a Mushroom Extract
The invention relates to anti-cancer compositions comprising synergistically effective amounts of an extract of shark meat and an extract of a mushroom, in particular, compositions containing a shark meat extract and an extract from the Korean mushroom Phellinus linteus. The invention also relates t
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Method of Identifying Individuals At Risk of Thiopurine Drug Resistance and Intolerance
The invention relates to methods and kits for identifying individuals at risk of thiopurine drug intolerance based on detecting the presence of mutations in the TPMT gene promoter associated with thiopurine drug resistance or intolerance.
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Detection of Volatile Compounds As Markers for Mycobacteria Tuberculosis
The invention relates to the use of biomarkers for identifying bacterial pathogens. In particular, the invention relates to the detection and identification of certain compounds as markers for mycobacterial infections in a patient or from a culture by analysis of a gaseous sample.
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Analysis System and Method
An analysis system has a sample region (1), a source of excitation radiation (3), and a wavelength-inspecific beam splitter (13) to deliver some of the excitation radiation to a sample. A dispersion element (2023) disperses returned radiation from the sample to be analysed that has been transmitted
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Nitric Oxide Donors
The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.
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An Apparatus and Method for Determining a Position of an Object
A method (300) and system for determining a position of an object is provided. The method (300) comprises receiving GPS data from two or more satellites (301). An actual signal characteristic associated with the GPS data is then determined (302). A set of signal characteristics being of a same type
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Analysing Breath Samples for Volatile Organic Compound
The invention describes the use of a biomarker pentylfuran to detect bacterial and/or fungal pathogens. Pentylfuran is released from certain pathogens and detected in the headspace gas of an in vitro culture or in the breath sample of a patient. Pentylfuran is particularly useful in the detection of
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Precision Weeders
The invention provides a method for intra-row and/or inter-row weeding of crop plants, and a controller and apparatus for achieving the same. The method is for tilling the soil between crop plants using a rotor device with a rotating tine rotor having a tine offset from an axis of rotation, a rotati
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Identification of Phosphorylation Sites in Polypeptides By Employment of Uranyl Photocleavage
The present invention relates to a method of cleaving a polypeptide at one or more phosphorylated residues. Said cleavage is induced by irradiation and is dependent on the presence of uranyl. The method is useful for analysis of phosphoproteoms and also for protein purification. The method also rela
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Flavin Monooxygenases and Transcription Factors Involved in Glucosinolate Biosynthesis
The invention provides methods and materials relating generally to plant derived flavin-containing monooxygenases (FMOs) capable of catalysing oxidation of a thio- to a sulphinyl- group during glucosinolate biosynthesis. It further relates to plant derived MYB factors capable of transcriptional regu
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Thermostable DNA polymerase of the archaeal ampullavirus ABV and its applications
The present invention is directed to the thermostable DNA polymerase protein of the archaeal ampullavirus ABV (Acidianus Bottle-shaped virus) and the nucleic acid encoding said DNA polymerase. The invention also relates to method of synthesizing, amplifying or sequencing nucleic acid implementing sa
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A Nucleotide Vaccine
The present invention relates to a vaccine comprising a nucleic acid construct such as a DNA construct especially a nucleic acid construct comprising sequences encoding invariant chain operatively linked to antigenic protein or peptide encoding sequences. The vaccine stimulates an immune response, e
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Inhibitors of Anorexic Lipid Hydrolysis for the Treatment of Eating Disorders
Compounds, pharmaceuticals, cosmetic or dietary supplements for the treatment of overweight, obesity and/or type II diabetes in a mammal (e.g. human) comprising a compound with formula I or formula II for example ceramidase-inhibitor, such as (1S,2R)-D-erythro-2-(N-myristoylamino)-1- phenyl-1-propan
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Porcine polymorphisms and methods for detecting them
Identification of a pig as resistant or non-resistant to enterotoxigenic E. Coli (ETEC). Particularly, there is provided methods, probes and DNA molecules involved in identifying a pig as resistant or non-resistant to ETEC. There is also provided methods for breeding pigs using the information of re
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A genetic marker test for brachyspina and fertility in cattle
This invention relates to methods for the detection of bovine that are affected by or carriers of Brachyspina (BS). The present invention provides a method for determining whether a bovine is affected by or carrier of BS by analyzing its genomic DNA or its RNA. The method can be used to perform mark
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Small Scale Solid State Screening
The present invention relates to screening of solid material. In particular the present invention relates to an apparatus and a method for screening of crystalline or amorphous material during secondary manufacturing. Accordingly the invention relates to a method for solid state screening by simulat
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Biosynthetic Engineering of Glucosinolates
The invention provides methods and materials, such as newly characterised genes, and novel processes, for converting a host from a phenotype whereby the host is unable to carry out glucosinolate (GSL) biosynthesis or chain elongation from an amino acid GSL-precursor to a phenotype whereby the host c
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Soluble Influenza Vaccine
The invention provides fusion proteins comprising: (i) a first portion comprising an influenza A M2e polypeptide, and (ii) a second portion comprising a rotaviral NSP4 polypeptide. The fusion proteins mimics the native tetrameric structure of native M2 protein. Additionally it is highly soluble and
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Dental Formulations for the Prevention of Dental Erosion
The invention relates to a therapeutic method for preventing and/or inhibiting dental erosion in a mammalian subject, and the provision of a dental care product for performing the method. The dental care product of the invention comprises a starch-degrading enzyme of E. C. 3.2.1.1, wherein said prod
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Electrochemical Flow Cell Detector
Electrochemical Flow Cell Detector comprising a chamber (1 ) configured to receive a first electrolyte solution; a membrane (2) comprising a second electrolyte in contact with the chamber, and in contact with the first electrolyte solution when present in the chamber; a first electrode (3) in fluid
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Stress-tolerant Plants Expressing Mannosylglycerate-producing Enzymes
The present invention provides compositions and methods for increasing the level of mannosylglycerate in plants. Plants with increased levels of mannosylglycerate exhibit enhanced tolerance to stress, e.g., drought
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Dna-based Methods for Clone-specific Identification of Staphylococcus Aureus
MRSA CC398 is a clone of S. aureus that has recently emerged in pigs and other domestic animals worldwide. As any other MRSA, the clone displays high levels of antibiotic resistance and poses a serious threat to human health because of the risk of antibiotic treatment failure in human patients. We d
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Use of Novel Biomarkers for Detection of Testicular Carcinoma in Situ and Derived Cancers in Human Samples
The present invention relates to methods and kits for identification of testicular carcinoma in situ (CIS), gonadoblastoma (a CIS-like pre-cancerous lesion found in dysgenetic gonads) and CIS-derived cancers based on at least one of the biomarkers included in the invention. It also relates to diagno
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A Genetic Marker Test for Brachyspina and Fertility in Cattle
This invention relates to methods for the detection of bovine that are affected by or carriers of Brachyspina (BS). The present invention provides a method for determining whether a bovine is affected by or earner of BS by analyzing its genomic DNA or its RNA. The method can be used to perform marke
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Method for Early Detection of Cancer
The present inventors have demonstrated that circulating auto-antibodies to cancer antigens hold promise as specific and sensitive biomarkers for the early detection of cancer. The present invention thus relates to methods of detecting cancer in a sample, comprising utilising a glycopeptide bait der
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Modified Peptides As Potent Inhibitors of the PSD-95/NMDA Receptor Interaction
The present invention is directed to the provision of small molecule inhibitors of the PSD-95/NMDA receptor interaction, employing an undecapeptide corresponding to the C-terminal of the NMDA as a template for finding lead candidates. A compound (NMDAR/PSD-95 inhibitor) of the invention includes a p
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Dehydrated Chitosan Nanoparticles
The present invention relates to dehydrated nanoparticles comprising chitosan and a nucleic acid. Preferably, the nucleic acid is a siRNA. Dehydrated nanoparticles of the invention have improved storage characteristics. The particles may be used in screening methods, e.g. where they have been dried
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Osteopontin Nanoparticles System for Drug Delivery
The present invention relates to nanoparticles comprising osteopontin and a polymer carrier, preferably a cationic carrier. Preferably, the cationic carrier is chitosan. Osteopontin and/or the cationic carrier may have bioactivity and/or the nanopar-ticle may comprise an additional component with bi
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Biocompatible Materials for Mammalian Stem Cell Growth and Differentiation
A biocompatible material, wherein at least a part of a surface of the biocompatible material is characterized by a micro or nano-meter scale topographical structure comprising a plurality of features where the structure is selected to promote the growth of undifferentiated pluripotent stem cells or
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Nanoparticle-mediated Treatment for Inflammatory Diseases
The present invention provides nanoparticles for treatment of inflammatory diseases. The nanoparticles preferably comprise chitosan and a siRNA targeting a mRNA encoding a pro-inflammatory cytokine, such as e.g. tnf-alfa. A preferred route of administration of the nanoparticles is by injection intra
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Selective Exosite Inhibition of PAPP-A Activity Against IGFBP-4.
The present invention relates in one embodiment to PAPP-A exosite(s) interactors such as antibodies which bind to a region comprising LNR3 of PAPP-A and efficiently inhibit proteolysis of IGFBP-4, but not -5. The region comprising LNR3 represents a substrate binding exosite, which can be targeted fo
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Method for diagnosis and treatment of a mental disease
The present invention relates to association of one or more polymorphisms in the human NHP2L1, PACSIN2, SERHL, PIPPIN, BRD1, EP300, FAM19A5 and/or GPR24 genes to the occurrence of schizophrenia and/or bipolar disorder. The invention relates both to methods for diagnosing a predisposition to said dis
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Methods for Determining a Breeding Value Based on a Plurality of Genetic Markers
The present invention provides a method for determining the individual effect of a plurality of genetic marker alleles on udder health, fertility and/or other health of a plurality of reference bovine subjects. The marker effects are employed in another aspect of the invention for determining a geno
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HIV-1 Envelope Polypeptides for HIV Vaccine
Immunogenic HIV-1 envelope polypeptides are provided, wherein specificamino acid residues are mutated to repress immunosuppression in GP41, thereby boosting the immune response against HIV-1. Specifically, mutation of those specific residues does not affect the fusogenic propertiesof the viral parti
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TFF3 Hypomethylation As a Novel Biomarker for Prostate Cancer
The present invention relates to a TFF3 gene as a marker of prostate cancer. The present invention thus relates to methods for diagnosing prostate cancer or predicting or prognosticating the disease outcome comprising steps of determining the methylation status of a TFF3 gene and/or the transcriptio
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Ionic Liquid Solvents
A chiral ionic compound comprising an alkyl substituted imidazolium or pyridinium cationic core having an alkyl ester side chain (-alkyl-C(O)O-) directly linked to the core and an associated counter anion, characterized in that the -O- atom of the ester side chain is linked to an alpha, a beta or a
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An Optical Wavelength Comb Generator Device
The present application relates to comb frequency generator devices generally and more particularly to the use of comb generators for use in fibre optic communications. More particularly, the application provides a frequency comb generator device. The device comprises a laser, a biasing circuit 26 f
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A Lateral Flow Assay Device for Coagulation Monitoring and Method Thereof
The present invention is directed to a lateral flow assay device for the monitoring and measuring of coagulation and method thereof. Ideally, the invention is directed to a lateral capillary flow device for the monitoring and/or measurement of coagulation in a liquid sample wherein the device compri
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Method of Surface Treating Microfluidic Devices
The formation of a barrier layer within individual channels or cavities of a microfluidic device is described. The barrier layer is effected through a gas phase deposition process, desirably implemented in a plasma environment.
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Compositions and Methods for Expressing In-frame Multimeric Proteins
The present invention concerns methods and compositions for making and using multimeric, single chain proteins of a defined structure. The invention also includes nucleic acid expression systems for making such multimeric proteins, and methods for identifying modulators of such multimeric proteins.
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Anti-sialic Acid Antibody Molecules
A method of generating and isolating a recombinant high affinity anti-sialic acid antibody molecule comprises the steps of immunising a host with an immunogen comprising a conjugate of sialic acid and a carrier protein to generate an anti-sialic acid polyclonal serum, isolating a sample of RNA from
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A Method of Predicting Response to Thalidomide in Multiple Myeloma Patients
A method of predicting response to thalidomide, or thalidomide analogs, in an individual with cancer, especially cancers for which thalidomide has been implicated as a treatment, such as Multiple Myeloma (MM) employs one or more of a panel of biomarkers that have been shown to be differentially expr
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System for analysing plasma
A system 400 for analysing plasma comprises at least one sensor 125 which is co-operable with a plasma generator for sensing a characteristic of plasma generated by the plasma generator and generating an analogue signal representative thereof. The system also includes an analogue-to-digital converte
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Electronic Cleansing of Digital Data Sets
A method of processing a 3-dimensional Computed Tomography Colonography data set to remove tagged material is disclosed. The method involves the preliminary processing step of classifying voxels in the data set as corresponding to air, tagged material or colon tissue. Methods of overcoming erroneous
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Dendrimer functionalised nanoparticle label
A label is disclosed comprising a nanoparticle wherein the nanoparticle surface is functionalised to comprise at least one dendrimer having at least one activatable functional group for conjugating a target analyte to the functionalised nanoparticle, wherein the dendrimer has a stabilising effect on
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Power Splitter
A power splitter comprising a transmission line and having at least one secondary winding(s) arranged about the transmission line, the transmission line operably providing a magnetic field which inductively couples power into the secondary winding(s) to provide a splitting of the power from the tran
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Ultra-compact Aperture Controlled Depth from Defocus Range Sensor
The present application teaches an implementation of an ultra-compact range sensor based on aperture varying passive depth from defocus (DFD). An embodiment of the present application teaches a range sensor, which is a fast LCD matrix that allows the acquisition of a plurality of images with variabl
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Optical Biochip Platform with Plasmonic Structure
Luminescent sensors which are configured such that operably plasmonic effects contribute to the output of the sensors are described. In a preferred arrangement there is provided a sensor having an optical element which operably effects generation of a luminescence signal for subsequent detection, th
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Biodegradable Solvents for the Chemical Industry
This invention relates to ionic liquid (ILs) solvents for chemical synthesis based on an alkyl - imidazolium cation core containing ionic liquids which have enhanced biodegradability and reduced toxicity relative to existing imidazolium bases ILs such as 1-butyl-3-methylimidazolium (bmmim) salts. Ma
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A Method of Assessing Cancer Status in an Individual
The invention relates to a method of screening patients to identify patients at risk of having a lung squamous cell carcinoma. A sample of serum from the individual is assayed for the abundance of a protein selected from the group consisting of: SEQUENCE ID NO'S: 1 to 11 relative for a control abund
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