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Self-assembling Multicellular Bodies and Methods of Producing a Three-dimensional Biological Structure Using the Same
Structures and methods for tissue engineering include a multicellular body including a plurality of living cells. A plurality of multicellular bodies can be arranged in a pattern and allowed to fuse to form an engineered tissue. The arrangement can include filler bodies including a biocompatible mat
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Modulating levels of RNA-binding proteins for the treatment of breast cancer
The present invention relates to methods of using RNA-binding protein modulating agents to treat of cancer, particularly patients that are susceptible to or diagnosed with estrogen receptor-negative breast cancer, such as methods of inhibiting the growth or metastasis of cancer cells comprising cont
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Hollow curved structures formed with friction stir welding
The present application describes a hollow structure, and a method of forming the hollow structure, where the hollow structure includes first and second metal parts (800), the second metal part (800) having an interior surface and a tapered support member (20) extending from the interior surface. Th
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Prediction and Diagnosis of Canine Degenerative Myelopathy.
The present invention provides for methods of identifying a dog carrying a major genetic risk factor in the SODl gene for degenerative myelopathy, a potential model for human amyeotrophic lateral sclerosis. Also provided a methods of early diagnosis, treatment and breeding based on the presence or a
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Corrosion-resistant Glasses for Steel Enamels
A cementitious composite material wherein glass-coated steel rods are positioned in a cementitious matrix. The glass composition for coating the steel reinforcing rods includes between about 33-45 weight percent SiO2, 13.5-19.5 weight percent B2O3, 3.5-4.6 weight percent A12O3, 4.0-13.5 weight perce
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Method and Apparatus for Cancer Screening
A method and apparatus for detection of pteridine levels in a biological sample using CE-LIF which is useful for early cancer screening involving fully oxidizing pteridine compounds in a sample such as a urine sample, subjecting to CE-LIF to assess compound concentration, and compare to expected lev
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High-throughput and Non-invasive Method to Vitrify Porcine Embryos
The present invention provides a practical, non-invasive, and efficient method for cryopreservation of an in-vitro-produced porcine embryo. The inventive method treats the IVP (such as IVF- or NT-derived) embryo at the one-cell or cleavage stage prior to compaction with high osmolality followed by h
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Novel Inhibitors of Retroviral Reverse Transcriptase
Disclosed are nucleic acid molecules, and methods of their use, which have a specific structure including a double helical domain and a G-quadruplex domain physically connected by a linker domain which may be nucleosidic or non-nucleosidic. These aptamers demonstrate potent inhibition of phylogeneti
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Assemblies for Use in Evaluating Subsurface Contamination, and Related Methods
A method is provided for determining the presence and/or concentration of at least one contaminant in a subsurface at a test site. The method generally includes inserting a sampling assembly into at least one tree at the test site, processing at least part of the sampling assembly to determine if a
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High Surface Area Carbon and Process for Its Production.
The present invention provides a high surface area porous carbon material and a process for making this material. In particular, the carbon material is derived from biomass and has large mesopore and micropore surfaces that promote improved adsorption of materials and gas storage capabilities.
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Supported Molecular Biofluid Viscosity Sensors for in Vitro and in Vivo Use
A device and a method for measuring viscosity that includes attaching molecular rotors to a solid surface, exposing the solid surface to a fluid having a viscosity to be measured, and taking optical measurements to determine viscosity. The solid surface is preferably quartz, polystyrene or silicate
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Phage Display Selection of Anti Fungal Peptides
A method for the identification of peptides having an affinity for the surface of fungi is provided as is a method for the identification of peptides capable of affecting the development of a fungus. Also provided are compositions containing peptides identified using the method of the present invent
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Assays for Detecting Pregnancy- Associated Glycoproteins
Disclosed are methods and compositions for detecting pregnancy in an animal by means of assaying peptidase activity of one or more Pregnancy Associated Glycoproteins (PAGs). In certain aspects, methods also comprising use of an antibody that binds immunologically to a PAG that displays proteolytic a
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Alteration of Phospholipase De (plde) Or Phospholipase Da3 (pld A3) Expression in Plants
Transgenic plants and seeds with altered expression of phospholipase De (PLDe) are described, i.e., plants and seeds either overexpressing or underexpressing PLDe. Methods for producing such transgenic plants and for increasing a plant's ability to capture and utilize nitrogen, increasing a plant's
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Method for detecting DNA methylation in cancer cells
The present invention provides a detecting method of detecting malignant cells in a patient's specimen or a biological sample. Specifically, the inventive method includes the steps of extracting a genomic DNA, digesting said genomic DNA with one or multiple methylation sensitive restriction enzymes,
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Nanocomposite Dielectric Coatings
The present invention describes processes for coating substrates with a nanocomposite SiCON material. In addition, the present invention describes the dielectric nanocomposite coatings.
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Method and Apparatus for Jet-assisted Drilling Or Cutting
An abrasive cutting or drilling system, apparatus and method, which includes an upstream supercritical fluid and/or liquid carrier fluid, abrasive particles, a nozzle (10) and a gaseous or low-density supercritical fluid exhaust abrasive stream. The nozzle (10) includes a throat section (2) and, opt
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Sensor Electrode and Method for the Electrochemical Detection of Nucleotides
A sensor electrode for the detection of nucleotides in a biological sample is described. The sensitivity of the electrode is enhanced by the nanostructured sensor architecture that increases the available surface area of the electrode. The electrode detects nucleotides using standard electrochemical
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Microwave and Millimeter Wave Imaging
A sensor array having a plurality of modulated slots for microwave and/or millimeter wave imaging. The locations of the slots in the array define a spatial domain away from an object for detecting an electric field from the object. Each of the slots outputs a signal representative of the measured fi
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Bacillus Based Delivery System and Methods of Use
Herein a Bacillus exosporium antigen delivery (BEAD) system that provides a means to introduce recombinant proteins or small molecules into the exosporium of members of the B. cereus family of bacteria, i.e. B. anthracis, B. cereus, and B. thuringiensis, is disclosed. The system results in the surfa
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Ultra-low Refractive Index High Surface Area Nanoparticulate Films and Nanoparticles
Nanoparticles having a mean particle size of less than about 25 nanometers and a mean pore size of less than 10 nanometers, and a mean surface area of at least 500 m2/g; nanoporous films of such nanoparticles; and composites and devices containing such nanoparticles and nanoporous films.
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Radioisotope Production and Treatment of Solution of Target Material
The invention provides methods for the production of radioisotopes or for the treatment of nuclear waste. In methods of the invention, a solution of heavy water and target material including fissile material present in subcritical amounts is provided in a shielded irradiation vessel. Bremsstrahlung
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System and Method for Harvesting Energy from Environmental Vibrations
Embodiments of the present invention provide a system and a method for increasing the harvested energy from a piezoelectric element exposed to environmental vibrations via a two-prong system. In a first prong, a cantilever beam is tapered and shaped so as to increase and provide an approximately uni
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Caffold for Bone and Tissue Repair in Mammals
A mammalian tissue scaffold and method for making a tissue scaffold including a rigid scaffold body of biocompatible glass fibers bonded together and in special alignment to define open channels within the scaffold to allow fluid flow into and within the scaffold.
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Drug Conjugates
Conjugated compounds comprising a therapeutic or diagnostic agent linked to a substrate for a cell membrane transporter or receptor by lipophilic linker are provided.
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Microfluidic Valve Systems and Methods
The present disclosure provides a microfluidic valve with a liquid-film-core to open and close one or more dispensing orifices of an ejection nozzle of a microfluidic system, such as an inkjet printhead, to prevent nozzle-clogging. The microfluidic valve employs a non-volatile liquid to control ambi
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System and Method for Linking a Web-based Resource with an Electronic Medical Record
A data processing system and method that, in some cases, include an EMR system and a web server. In some cases, the EMR system includes a plurality of electronic medical records for a plurality of patients. One or more of the electronic medical records may include a URL or HTTP Post message that def
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Compounds for Treatment of Copper Overload
The present invention provides compounds, pharmaceutical compositions, and methods that can be used to treat pathologies that are due to copper overload or to the presence of reactive oxygen species.
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Convection Battery Configuration for Connective Carbon Matrix Electrode
Electrode compositions and devices (100) that incorporate the electrode compositions are provided. More specifically, electrode compositions that include carbon that provide a connective network to which metal and/or metal derivatives are deposited are provided. Convection battery devices (100) that
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Separation Method for Carrier-free Radiolanthanides
A method for separating a lanthanide from a mixture containing at least one other lanthanide is provided. In particular, an HPLC and liquid separation method using a chromatographic column for separating a lanthanide from a mixture containing at least one other lanthanide is provided.
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Calcium Phosphate Bodies and a Process for Making Calcium Phosphate Bodies
Among the various aspects of the present invention is a process for making calcium phosphate bodies comprising amorphous calcium phosphate, hydroxyapatite or calcium triphosphate, the bodies themselves and the use of such bodies in any of a variety of applications.
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Non-destructive Rotary Imaging
Non-destructive imaging of an object. An imaging head supported on a rotatable arm samples an electric field scattered by the object at a plurality of locations as the arm rotates about a central axis, with the locations corresponding to a defined spatial domain located remotely from the object. One
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Hollow Structures Formed with Friction Stir Welding
A hollow structure, and a method of forming the hollow structure, where the hollow structure includes first and second metal parts, the second metal part having an interior surface and a tapered support member extending from the interior surface. The hollow structure also includes a friction stir we
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High Frequency Analysis of a Device Under Test
Analyzing a device under test ("DUT") at higher frequencies. A phase shifter varies the phase of a standing wave on a transmission line coupled to the DUT. The standing wave magnitude is sampled at each of the phase shifts and one or more DUT characteristics are determined as a function of the sampl
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Rotator Cuff Bone-tendon Allograft
The invention provides a biomaterial and a method of selecting a biomaterial for a rotator cuff repair procedure. The biomaterial includes a bone-tendon allograft and the use of the biomaterial in rotator cuff repairs may provide immediate bone-tendon integrity and function, which may result in lowe
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Soy-based Polyols
The invention provides B-sides of urethane formulations, wherein the B-sides comprise both alcohol and epoxy moieties. Also provided are urethane formulations comprising the B-side of the invention, as well as A-sides comprising isocyanate molecules.
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Adaptive Lens for Vision Correction
An adaptive liquid crystal lens system comprising a first substrate assembly, a second substrate assembly having a continuous phase profile, and a liquid crystal layer disposed between the first and second substrate assemblies. The first substrate assembly includes a first transparent substrate, an
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High Energy-density Radioisotope Micro Power Sources
A method of constructing a solid-state energy-density micro radioisotope power source device (10). In such embodiments, the method comprises depositing the pre-voltaic semiconductor composition (38A), comprising a semiconductor material and a radioisotope material, into a micro chamber (28) formed w
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Optical Spectroscopy Device for Non-invasive Blood Glucose Detection and Associated Method of Use
An apparatus for concentrating light and associated method of use is disclosed. This apparatus includes a first outer wall having an anterior end, a posterior end, an inner surface and an outer surface, the inner surface defining an interior portion, the interior portion having an anterior end and a
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Mass Sensing Device for Liquid Environment
A device for sensing a mass in a liquid environment including a resonator comprising a piezo layer having a top electrode and a bottom electrode, a sensing surface located adjacent and opposite the top electrode, the resonator and the sensing surface defining a gap therebetween, and a post attached
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Immunoassay for Venom Detection Including Noninvasive Sample Collection
Methods and immunoassays for diagnosing a bite or sting of a venomous organism in a patient having symptoms consistent with such a bite or sting are provided. A sample of venom is collected from the area of the suspected bite or sting using a swab and then contacted with an antibody that specificall
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Photoacoustic Detection of Analytes in Solid Tissue and Detection System
A preferred system for detecting an analyte in solid tissue (12), such as an intact lymph node, in vitro includes a laser (22) arranged to generate a pulsed laser beam into solid tissue, which can be a fully intact lymph node. An acoustic sensor, and preferably at least three acoustic sensors (20a,
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Atmospheric Non-Thermal Gas Plasma Method for Dental Surface Treatment
The provision of dental restorations can be improved by generating a cold atmospheric plasma inside the mouth of the patient and then applying that cold atmospheric plasma onto a dental restoration site. The dental restoration site can be composed of either or both of dentin and enamel. Further, the
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Treatment of Type 1 Diabetes Before and After Expression of Predisposition Markers
The present invention relates generally to the use of compounds, compositions, combinations, kits, and methods for the effective endocytic presentation of immunosuppressive factors for the down regulation of diabetogenic T cells for the treatment of type 1 diabetes.
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Circuit and Method to Suppress the Parasitic Resonance from a Dc/dc Converter
A snubber circuit for use with a DC/DC converter broadly comprises a snubber resistor connected in parallel with a snubber inductor. The DC/DC converter may include a voltage source, a first switching element, a second switching element, an output inductor, and an output capacitor. The voltage sourc
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Integrated Sensor Network Methods and Systems
Methods and systems for an integrated sensor network are described. In one embodiment, sensor data may be accessed from a plurality of motion sensors and a bed sensor deployed in a living unit for a first time period. An activity pattern for the first time period may be identified based on at least
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Microwave and Millimeter Wave Resonant Sensor Having Perpendicular Feed, and Imaging System
A switched-slot sensor for use in a sensor array for microwave and/or millimeter wave imaging. The locations of a plurality of sensors in the array define a spatial domain away from an object for detecting an electric field from the object. Each of the sensors has an out-of-plane transmission line a
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Photo-acoustic Detection Device and Method
An example system for detecting an analyte in a sample of a bodily fluid comprises a test chamber having at least one sidewall and configured to contain at least a portion of a bodily fluid sample, an excitation electromagnetic energy source configured to direct an energy source into the test chambe
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Drought Responsive Genes in Plants and Methods of their Use
Microarrays are employed to analyze soybean transcriptions under water stress conditions in both root and leaf tissues at vegetative stage. Novel drought responsive genes may be thus identified and may be used for enhancing drought tolerance in soybean or other plants through genetic/metabolic engin
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Agarose Nano-platinum Composite
The invention relates to compositions and methods of using electrophoresis separation matrices. The invention provides nano-particle comprising separation matrices having increased conductivity at low voltage.
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Acyclovir-peptide Analogs
Dipeptide and tripeptide ester derivatives of acyclovir and its analogs are disclosed which are useful to treat herpes virus infections. Also disclosed is a method for preparing a therapeutic agent for targeted delivery to ocular tissue comprising linking the therapeutic agent to one or more groups
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Soy or lentil stabilized gold nanoparticles and method for making same
The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from soy or lentil plant material or a reactive extract thereof of the plant material. The gold nanoparticles of the invention can be fabricated with an environmentally friendly method for making bi
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Revising Imagery Search Results Based on User Feedback
A method, system, and medium are provided for revising a first set of search results related to high-resolution satellite imagery. One embodiment of the method includes receiving a query that seeks high-resolution, remotely sensed images of geographic areas that have changed consistent with a given
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Plant Artificial Chromosome Platforms Via Telomere Truncation.
The invention provides engineered plant minichromosomes generated by telomere mediated truncation of native chromosomes. These minichromosomes are faithfully transmitted from one generation to the next and provide an ideal platform for breeding genes into desired plant varieties with out problems, s
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Stereochemically Defined Dipeptide Esters of Antiviral Agents for Enhanced Ocular Treatment
Stereochemically defined dipeptide esters of nucleoside-analogous antiviral agents including acyclovir and ganciclovir are provided. Certain of these stereochemically defined dipeptide esters are found to have unexpectedly enhanced delivery to and uptake by ocular tissues, crossing the blood-ocular
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Electromagnetic Emissions Stimulation and Detection System
A system and method for detecting and identifying electronic devices based on their unintended electromagnetic emissions ("UEE") signals is presented. During device classification, UEE signals are measured from a plurality of test devices and characteristic data is obtained from the UEE signal emitt
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Light Scattering Detector
The invention concerns high sensitivity light scattering detection and its application to evaporative light scattering detection in liquid chromatography. The exemplary embodiment includes a detection cell to accept particles suspended in a gas stream and permit a polarized light beam to pass throug
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Mutants of the P4 Protein of Nontypable Haemophilus Influenzae with Reduced Enzymatic Activity
A P4 variant protein that has reduced enzymatic activity and that induces antibody to wild-type P4 protein and/or has good bactericidal activity against non-typable H. influenzae (NTHi) is useful as an active component in an immunogenic composition for humans. Methods of using these proteins, and co
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Stabilized Gold Nanoparticle and Contrast Agent
A kit for providing a contrast enhancer in a mammal for contrasting during imaging of the mammal comprises functionalized gold nanoparticles configured to be directed to one or more of a target organ, tissue and lesion of the mammal.
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Noise Cancellation in Fourier Transform Spectrophotometry
Increasing signal to noise ratio in optical spectra obtained by spectrophotometers. An interferometer introduces interference effects into a source light beam. A dual beam configuration splits the source beam having the interference effects into a reference beam and a sample beam. The reference beam
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Pre-formed Assemblies of Solgel-derived Nanoparticles As 3-d Scaffolds for Composites and Aerogels
A composite material that includes a dopant comprised of pre-formed, three dimensional assemblies of skeletal structures that are comprised of solgel derived nanoparticles. The composite material includes a chemically bonded, in situ formed, polymer coating that at least partially coats mesoporous s
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Monolithic Polymer Crosslinked Composite Materials and Methods of Making
A bidentate free radical crosslinking initiator binds chemically to silica and silica rich surfaces and enables the free radical based polymerization of various materials such as styrene, divinylbenzene and methylmethacrylate onto silica and silica rich surfaces. When used in connection with aerogel
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Synthetic Osteochondral Composite and Method of Fabrication Thereof
An osteochondral composite (10) including a hydrogel (24) with implanted biological cells (26) joined to a porous supportive base (12) at a mechanically-interlocked interface is disclosed. A method of fabricating the osteochondral composite (10) and a method of treating damaged or diseased articular
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A Device for Transfecting Cells Using Shock Waves Generated By the Ignition of Nanoenergetic Materials
A miniature device for generating shock waves using the energy of combustion of a nanoenergetic material and directing the shock waves into biological tissues is described.
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Optical Device Components
Embodiments of the invention relate to an apparatus including a light source to generate a plurality of light beams with each of the plurality of light beams having a different wavelength range. The apparatus also includes a light funnel to direct the plurality of light beams to the target area, an
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Pharmaceutical Composition Comprising a Proton Pump Inhibitor and Protein Component
The present disclosure relates to, inter alia, pharmaceutical compositions comprising a H+,K+-ATPase proton pump inhibitor and a protein component; to methods for manufacture of such compositions, and to use of such compositions in treating and preventing diseases and/or disorders.
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Thermally Driven Heat Pump for Heating and Cooling
A thermally driven heat pump includes a low temperature evaporator for evaporating cooling fluid to remove heat A first heat exchanger located at an outlet of a converging/diverging chamber of a first ejector receives a flow of primary fluid vapor and cooling fluid vapor ejected from the first eject
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Oral Antidepressant Formulation
TriRima® Product Profile
Summary
TriRima® is an optimized, specific, high affinity, reversible inhibitor of monoamine oxidase-A (RIMA) potentially useful as monotherapy in the treatment of major depressive disorder. TriRima was designed and developed specifically to maximize RIMA efficacy while
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Improved Continuous Variable Transmission System and Use Thereof
The HP-CVT is a patent-pending redesigned continuously variable transmission (CVT) for use in vehicles and other motorized applications, with unique capabilities in high power/high torque contexts (thus the name—HP-CVT) such as for use in large vehicles and machinery. The HP-CVT functions not only
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Three-dimensional Lidar-based Clear Path Detection
A method for detecting a clear path of travel for a vehicle includes generating a datastream corresponding to a three-dimensional scan of a target area surrounding the vehicle from a vehicle LIDAR system, estimating a ground plane for a present vehicle location using the datastream corresponding to
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Clear Path Detection Using an Example-based Approach
A method for detecting a clear path of travel for a vehicle using a current image generated by a camera includes defining an exemplary clear path for each of a plurality of sample images, identifying features within each of the plurality of sample images, monitoring the current image generated by th
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Clear Path Detection Using Patch Approach
A method for detecting a clear path of travel for a vehicle utilizing an image generated by a camera device located upon the vehicle includes monitoring the image, and generating a plurality of patches onto the image, wherein the patches are collectively arranged to substantially include the clear p
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Clear Path Detection Using a Vanishing Point
A method for estimating a vanishing point in a roadway using a current image generated by a camera on a vehicle includes defining an exemplary vanishing point for each of a plurality of sample images, identifying features within each of the plurality of sample images, monitoring the current image ge
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Chiral Indole Intermediates and their Fluorescent Cyanine Dyes Containing Functional Groups
This invention relates to the functionalized cyanine dyes and more particularly, to the synthesis of chiral 3-substituted 2,3'-dimethyl-3H-indole and its derivatives as intermediates for preparation of cyanine dyes, to methods of preparing these dyes and the dyes so prepared.
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Buffer Layers for L10 Thin Film Perpendicular Media
A process of fabricating a perpendicular magnetic recording medium. In one embodiment, the process may comprise forming a metallic buffer layer with a (002) texture on an underlayer using a deposition process performed at a temperature below 30 DEG C. The underlayer may have a crystalline (001) text
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Drawing Assist Device, Drawing Assist Program, and Drawing Assist Method
Provided is a drawing assist device and the like which assists a drawing operation while improving efficiency thereof. According to the drawing assist device of the present invention, whether or not a first factor of an element defined according to a positional trajectory of a pointer moved by an ag
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Purification Methods and Purified Conjugated Polymers
Metal complexing agents are used to purify polymers including conducting polymers to provide very low metal content. The process comprises precipitating the polymer in solution into a solvent system comprising the metal complexing agent. Very low levels including undetectable levels of metals such a
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Simultaneous Bit Pattern Determination and Head Positional Information Detection on Patterned Media
An apparatus, system, and method comprise a magnetoresistive head configured to respond to magnetization states of patterned cells formed on a patterned medium. The magnetoresistive head detects the magnetization states of at least two patterned cells formed on a patterned medium. The magnetoresisti
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Improved Controlled Radical Polymerization Processes
A transition metal mediated chain transfer agent controlled polymerization process is described. The process combines the advantages of atom transfer radical polymerization (ATRP) and reversible addition fragmentation transfer (RAFT) polymerization. Synthesis of chain transfer agents useful in the d
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Method of Assessing a Body Part
A method of assessing a body part includes obtaining two or more types of data through a combination of two or more of the following four imaging modalities: (1) obtaining surface topography data of the body part, (2) obtaining thermographic data of the body part, (3) obtaining range of motion data
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Antenna with Multiple Co-located Elements with Low Mutual Coupling for Multi-channel Wireless Communication
An antenna that has a number of co-located elements, with no (or very small) coupling between the various elements. The antenna may comprise one or more electric dipole elements, such as an electric tripole, co-located with one or more magnetic dipole elements, such as a magnetic tripole. The antenn
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Linked Peptide Fluorogenic Biosensors
Biosensors, compositions comprising biosensors, methods of producing biosensors, and methods of using biosensors are disclosed. The biosensors comprise a fluorogen- activating peptide and a blocking peptide. The fluorogen-activating peptide and blocking peptide are covalently linked through a peptid
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Drawing Support Device, Drawing Support Program, and Drawing Support Method
The present invention provides a device capable of supporting drawing work while improving the continuity of the drawing work. According to a drawing support device 1, components corresponding to successive position trajectories of the tip of a pen 2 are displayed on a panel 3, and this enables draw
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Efficient High Performance System for Writing Data from Applications to a Safe File System
Systems and methods for increasing the efficiency of data storage processes for high performance, high core number computing systems. In one embodiment, the systems of the present invention perform sequential I/O whenever possible. To achieve a high degree of sequentiality, the block allocation sche
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Living Synthesis of Conducting Polymers Including Regioregular Polymers, Polythiophenes, and Block Copolymers
Regioregular poly(3-alkylthiophenes) and other polythiophenes can be prepared by living polymerization which have good solubility, processability and environmental stability. The polymerization method can afford regioregular poly(3-alkylthiophenes) in high yields. Kinetic study of polymerization rev
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Methods and Apparatuses for Monitoring Energy Consumption and Related Operations
Apparatus and method including acquiring a signal indicative of power consumption; detecting a transient in the signal; extracting a feature indicative of the transient, wherein extracting the feature includes: fitting a plurality of models to the transient, selecting one of the plurality of models
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Systems and Methods for Managing Power Consumption and Performance of a Processor
Processor-management techniques that purposely alternate a processor between an operating state and a non-operating state while the processor is executing the workload. The techniques leverage the "ultra-low-power" non-operating states of many processors to provide predictable power and/or frequency
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Systems and Methods for Implementing a Machine-Learning Agent to Retrieve Information in Response to a Message
Mixed-initiative message-augmenting agent systems and methods that provide users with tools that allow them to respond to messages, such as email messages, containing requests for information or otherwise requiring responses that require information that needs to be retrieved from one or more data s
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Articulated Device with Visualization System
An articulated device may include a first steerable multi-linked mechanism and a second steerable multi-linked mechanism. The second steerable multi-linked mechanism may include a first link, a plurality of intermediate links and a second link movably coupled to a second one of the intermediate link
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Multi-linked Endoscopic Device with Spherical Distal Assembly
A device for performing a procedure may include an elongate tube having a proximal end and a distal end and an adapted link having a proximal end and a distal end. The distal end may include a first mating surface, where the proximal end may be configured to attach to the distal end of the elongate
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Antibodies and Conjugates for Modulators of Angiogenesis
We provide methods and compositions for the treatment of dysregulation of blood vessel growth by regulation of neovascularization. Embodiments accomplish this by restricting the diffusion and transport of therapeutic agents through conjugating them to polymers or polymer constructs while retaining t
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Magnetically-levitated Blood Pump with Optimization Method Enabling Miniaturization
A magnetically-levitated blood pump with an optimization method that enables miniaturization and supercritical operation. The blood pump includes an optimized annular blood gap that increases blood flow and also provides a reduction in bearing stiffness among the permanent magnet bearings. Sensors a
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Metal Ink Compositions, Conductive Patterns, Methods, and Devices
Metal complexes adapted to form conductive metal films and lines upon deposition and treatment. The metal complex can be a covalent complex and can comprise a first and second ligand. Low temperature treatment can be used to convert the complex to a metal. The metal films and lines can have low resi
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Cellular labeling for nuclear magnetic resonance techniques
The disclosure provides, in part, fluorocarbon imaging reagents and formulations for the ex vivo labeling of cells. Labeled cells may be detected in vivo or ex vivo by a nuclear magnetic resonance technique, such as magnetic resonance imaging (MRI) or magnetic resonance spectroscopy (MRS). The discl
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Inflammation-regulating Compositions and Methods
The various embodiments provide a composition that provides local control over inflammation. The composition localizes the activities of the cytokine-neutralizing antibodies to the site of inflammation through covalent attachment to hydrophilic matrices. The various embodiments including a hydrophil
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Robotic System Including Foldable Robotic Arm
A system includes an end effector (110), a robotic wrist (120) for orienting the end effector (110); and a robotic arm (130) for positioning the end effector. The robotic arm (130) is foldable into a stack. The robotic wrist (120) is mounted to a last link of the robotic arm.
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Methods and Apparatuses for User-verifiable Trusted Path in the Presence of Malware
An apparatus and method for establishing a trusted path (152) between a user interface (150) and a trusted executable (312), wherein the trusted path (152) includes a hypervisor (316) and a driver shim (314). The method includes measuring (710) an identity of the hypervisor; comparing (712) the meas
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Sodium Ion Based Aqueous Electrolyte Electrochemical Secondary Energy Storage Device
A secondary hybrid aqueous energy storage device includes an anode electrode, a cathode electrode which is capable of reversibly intercalating sodium cations, a separator, and a sodium cation containing aqueous electrolyte, wherein an initial active cathode electrode material comprises an alkali met
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Luminescent Multimodal Nanoparticle Probe System and Method of Manufacture Thereof
A method of manufacture of a luminescent nanoparticle probe system includes forming a bismuth sulfide core; and coating the bismuth sulfide core with a shell.
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Apparatuses, Systems, and Methods for Apparatus Operation and Remote Sensing
A method and system for controlling an apparatus including receiving data indicative of an actual state of the apparatus, defining a first viewpoint relative to at least one of the environment and the apparatus, determining a first predicted state of the apparatus at time T, determining a first pred
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