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Actuator Powered Deformable Soft-bodied Autonomous Platforms
The present solution described herein provides apparatuses, methods and systems for coordinating and controlling movement of soft-bodied robots, or soft-bodied platforms. A soft- bodied robot may move across a terrain by morphing, deforming, expanding, shrinking, extending, contracting, twisting, un
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Indole Compounds and Methods of Use Thereof
Novel indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
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Methods and Apparatus for Visual Sub-band Decomposition of Signals
Methods and apparatus for image processing include performing visual sub-band decomposition of an image using human visual system characteristics to generate a plurality of sub-band decomposed images, independently processing the plurality of sub-band decomposed images with at least one application,
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Methods and Apparatus for Image Restoration
Methods and apparatus for restoration of a digital image. In one embodiment, a method for repairing a defect in a digital image to provide a restored image comprises determining a plurality of pixel locations to form a neighborhood relating to the defect and whether or not the neighborhood has a wel
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Mems Microphone Array on a Chip
The present invention relates to microelectromechanical systems (MEMS). In particular, the present invention relates to MEMS arrays for use in acoustics and other applications.
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Design of Dynamic Experiments for the Modeling and Optimization of Batch Process
The present invention relates to systems and methods for the dynamic design of experiments for modeling and optimization of batch processes in a wide variety of fields. In particular, the present invention provides systems and methods for identifying, selecting, implementing, and improving upon batc
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Smad Proteins Control Drosha-mediated Mirna Maturation
The invention, in some aspects, relates to compositions and methods useful for modulating expression of miRNAs that are regulated by the TGF-ss/BMP signaling pathway. In some aspects, the invention relates, to oligonucleotides comprising a CAGRN-motif that modulate expression of miRNAs that are regu
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Methods and Compositions for Spore-based Vaccines
Methods for immunizing a subject to an infectious agent are provided, using vegetative cytoplasmic expression of an antigen encoding an infectious agent or spore surface display of the antigen, and contacting the subject with a composition including a spore or a vegetative cell or both with or witho
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Method for Assessing Potential for Tumor Development and Metastasis
The present invention generally provides methods for assessing the potential of tumor formation and/or metastasis using a combination (e.g., a ratio) of the number of circulating tumor cells and the number of circulating cells exhibiting autofluorescence within a selected wavelength region (e.g., re
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Genetic Markers for Obesity
The present invention is directed to new genetic variants or polymorphisms at the perilipin locus (PLIN) including PLIN1: 6209T (allele 1)>C (allele 2); PLIN3 10171 (allele 1) A >T (allele 2); PLIN4: 11482G (allele 1)>A (allele 2); PLIN5: 13041A (allele 1)>G (allele 2) and PLIN6: 14995A (allele 1)>T
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Method and Composition for Inhibiting Multi-drug Resistance By Hyaluronan Oligomer
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for treating multi-drug resistant cell. ; SOLUTION: The pharmaceutical composition includes a competing agent of hyaluronan interaction with an effective dosage in order to reduce the cellular tolerance against a pharmacologic agent. As t
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Measurement of Biological Targets
An integrated imaging system, e.g., a microsystem, for detecting activity of a biological target, for example, in response to a stimulus, includes an array of pixels arranged on a substrate, each pixel including a photodetector disposed to be in optical communication with a biological target on a su
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Treating Catalysts
A method includes contacting a catalyst including a metal having an average particle size of approximately one nanometer or greater with SO2; and reducing the average particle size of the metal.
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Method and System of Array Imaging
The present invention relates to a method and system of array imaging that extends or maximizes the longevity of the sensor array by minimizing the effects of photobleaching. The imaging system has a light source, a variable exposure aperture, and a variable filter system. The system extends the lon
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Spectroscopic Imaging Microscopy
Disclosed herein are systems that include: (a) an objective lens system configured to collect light from a sample; (b) a first aperture positioned to allow a portion of the collected light received from the objective lens system to pass as input light; (c) a first lens positioned to transmit the inp
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Methods and Compositions for Inhibiting Clostridium Difficile Spore Germination and Outgrowth
Certain bile acids, including novel bile acids, and derivatives thereof can be used to inhibit the germination of C. difficile spores and/or the growth of C. difficile cells. The methods and compositions of the invention are useful for preventing and treating C. difficile-associated diseases, includ
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Iron-mediated Remediation Within Nonaquous Phase Liquid
The present invention relates to remediation of hazardous waste sites. In particular, the present invention relates to compositions and methods for remediation of environmental contaminants in non-aqueous phase liquids (NAPLs).
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Methods and System for Confocal Light Scattering Spectroscopic Imaging
The present invention is generally directed to imaging methods and apparatus that employ angular and/or wavelength distribution of light backscattered from multiple portions of a sample in response to illumination by electromagnetic radiation to generate one, two or three dimensional images of the s
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Methods and Compositions for Modulating Membrane Potential to Influence Cell Behavior
The present invention provides methods for controlling proliferation, differentiation, and/or migration of cells by modulating membrane potential through an endogenously expressed channel protein. The present invention also provides methods for identifying candidate instructor cells, as well as ther
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Methods and Compositions for Promoting Regeneration By Increasing Intracellular Sodium Concentration
The invention provides methods and compositions for increasing the intracellular sodium concentration in a cell.
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Small Molecule Antagonists of Phosphatidylinositol-3, 4, 5-triphosphate (pip3) and Uses Thereof
Disclosed are a new class of non-lipid small molecule inhibitors which interfere with the interaction between PIP3 and pleckstrin homology domains. These molecules target a broad range of PIP3 -dependent signaling events in vitro and exert significant anti-tumor activity in vivo. The small molecule
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Genetic Association of Polymorphisms in Perilipin (plin) Gene with Resistance to Weight Loss
Diagnostics and therapeutics for resistance to weight-loss, which are based upon the identification of a subject's PLIN polymorphisms, haplotype and genotype pattern, are described in this invention.
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Methods, Apparatuses, and Kits for Introducing Genetic Material Into Living Cells
Methods, kits and devices are provided for introducing genetic material into cells, including post-mitotic types of cells such as neurons and sperm cells. The methods and devices utilize high fluid velocities, and cell survival following treatment by the methods including the loading process is enha
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Method for Fitting a Parametric Representation to a Set of Objects
Described is a method for fitting a parametric representation to digital data. A vector distance field is generated to represent a set of objects and a parametric representation for the set of objects is initialized. A fitting error is determined from the vector distance field representation. The fi
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Polymeric Microspheres
The invention features core-shell microsphere compositions, hollow polymeric microspheres, and methods for making the microspheres. The microspheres are characterized as having a polymeric shell with consistent shell thickness.
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Analysis of Endogenous Fluorescence Images to Extract Morphological/organization Information About Living Samples
Methods and computer program products for analyzing tissue are provided. The tissue is exposed to light at the appropriate wavelengths for inducing fluorescence. Images of the fluorescing tissue are taken at two or more depths within the tissue. The PSD function is determined for each image at a dif
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Cholera Vaccines
The methods and compositions of the present invention are directed to a vaccine against Vibrio cholerae comprised of V. cholerae outer membrane vesicles (OMVs). Such vaccines are relatively stable, facilitating distribution. Inventive methods generally include administration of a vaccine against Vib
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Fluorinated Lipids and Methods of Use
The invention provides methods and compounds for delivering agents to cells. The compounds can include a fluorinated lipid, a linker, and an agent for delivery to a cell.
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Method for Recognizing a Shape from a Path of a Digitizing Device
Described is a method for recognizing a shape from a path of a digitizing device. A set of points along a path of the digitizing device is acquired and a parametric representation is fit to the path. The parametric representation is compared to a set of known shapes to determine that the path of the
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Systems, Devices, and Methods Employing Fiber Optic Shape Tracking
The present invention provides systems, devices, and methods employing fiber optic shape and position tracking. The systems, devices, and methods permit measurement of and continuous tracking of the shape and position of objects whose shape dynamically changes with time. Applications include trackin
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POI Prevention
A method is provided, comprising administering at least one guanylhydrazone or salt thereof or a combination thereof to a subject to prevent or ameliorate in said subject at least one of postoperative intestinal inflammation, postoperative ileus, ischemia reperfusion injury, or a combination thereof
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Androgenetic Alopecia
The present invention relates to methods for testing for a predisposition or presence of androgenetic alopecia comprising testing a sample obtained from a prospective patient or from a person suspected of carrying a predisposition for androgenetic alopecia. The invention also relates to a genetic ma
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In-vivo Stimulation Measuring Probe
The invention relates to a measuring probe and a system for the targeted optical in-vivo stimulation of nerve cells and for the electrical measurement of nerve cell pulses. The measuring probe comprises at least one measuring needle for automatically controlled, motorized in-vivo insertion into a br
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Enantioselective production of alpha-hydroxy carbonyl compounds
The invention relates to a process for the regioselective and enantioselective preparation of +--hydroxy carbonyl compounds from +--ketocarbonyl compounds via enzymatic reduction.
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Light Source and Method for Producing Light
The invention relates to a light source, comprising an optical resonator (1) and an optical medium (2) arranged therein that can be excited so as to emit light, wherein the optical medium (2) comprises at least one two-level system, in particular a two-level system that is not population-inverted, h
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Pharmaceutical Composition Containing Cannabinoid-receptor Antagonists
The present invention relates to the use of cannabinoid-receptor 2 (CB2R)-antagonists for the prophylaxis and/or treatment of pathogen, in particular, parasitic protozoa, caused or induced cerebral diseases, disorders or conditions including secondary and accompanying diseases, disorders or conditio
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Anti-HSV antibody
The invention relates to an anti-HSV antibody as defined in the claims, a pharmaceutical composition comprising of an effective amount of the said antibody, an expression vector comprising of a nucleotide sequence which encodes the said antibody, a host cell comprising of the said nucleotide sequenc
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Adenine Receptor Ligands
The invention relates to adenine receptor ligands useful for treating, alleviating and/or preventing diseases and disorders related to adenine receptor function as well as pharmaceutical compositions comprising such compounds and methods for preparing such compounds. The invention is further directe
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PPAR gamma agonists for treating illnesses with pathophysiological participation of TH17 lymphocytes
Use of one or more peroxisome proliferator-activated receptor (PPAR)-gamma agonists for treating a disease in which T helper 17 (TH17) cells have a pathophysiologically relevant function, is claimed. - ACTIVITY : Antiarthritic; Antirheumatic; Antipsoriatic; Neuroprotective; Antiinflammatory; Gastroi
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Non-wettable Surfaces
An object having a surface that has: filaments having a length of from 30 to 6000 [mu]m, a diameter to length ratio of from 1:10 to 1:20, and are bound to the surface with at least one front face thereof; wherein the distance between two neighboring filaments on the surface is such that the ratio of
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New nucleic acid molecules and polypeptides involved in lipid metabolism
The present invention relates in a first aspect to polypeptides useful for the prevention or treatment of various diseases. In particular, the present invention relates to a polypeptide containing a homeodomain for the prevention or treatment of lipid-based metabolic diseases, cancer, (neuro)degener
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Cytohesin Inhibitors
The present invention relates to a pharmaceutical preparation comprising as an active ingredient a primary amide according to the general formula (1) and/or a secondary amide according to the general formula (2) and their use as a medicament.
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Nucleic Acid Expression Construct and Its Use As a Cell Proliferation Marker
In a first aspect, the present invention provides a nucleic acid expression construct encoding a fusion protein comprising a reporter protein and a protein with a wild-type destruction signal, wherein the sequence encoding the fusion protein is operably linked to a non-endogenous promoter, and where
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INHIBITORS OF THE NITRATION OF AMYLOID ss PEPTIDES AND THEIR USES IN THE DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE
The present invention relates to a method for identifying an inhibitor of the aggregation of amyloid-ss peptide (Ass), comprising the steps of a) contacting at least one Ass-peptide and/or the nitrated forms thereof with at least one candidate inhibitor that potentially specifically binds to a regio
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Odor Samples of Peroxidic Explosives
The invention relates to the use of a neutral ionic liquid for stabilizing peroxidic explosives and for producing stable solutions of peroxidic explosives. The invention further relates to stable compositions comprising a solution of a neutral ionic liquid having a detectable quantity of a peroxidic
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Apparatus and Method for Detecting Triacetone Triperoxide
The present invention relates to an apparatus and method for fast and secure online detection of triacetone (TATP).
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Anticancer Agent
The present invention relates to a pharmaceutical composition for the therapeutic and/or prophylactic treatment of cancer and/or metastasis thereof comprising an amino acid sequence related to a Wech protein and/or a nucleic acid sequence of the gene encoding for the Wech protein.
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Sensor Arrangement
The invention relates to a sensor arrangement for detecting electromagnetic radiation whose wavelength in or near the infrared range, with at least one measuring chamber (2), which is filled with the radiation to be measured selectively absorbing fluid, the measuring chamber (2) by a windows (3) sea
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Method and Apparatus for Generating Two Light Waves which Have Stable Frequencies Relative to One Another
The invention relates to a method for generating two light waves (3, 11) which have stable frequencies relative to one another, in which method an accumulation of particles of a lambda system is illuminated by a control light beam (3) and a first signal light beam (4), wherein the control light beam
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Identification of Regulatory T Cells Via the Global Gene Regulator Satb1
The present invention provides a method for the identification of regulatory T cells based on the diminished abundance or even absence of the global gene regulator SATB1 in such regulatory T cells. In particular, the invention relates to a method utilizing ligands that specifically bind to SATB1 for
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Method for Obtaining Human Microglial Precursor Cells from Pluripotent Stem Cells
The present invention relates to a method for obtaining human microglial precursor cells, comprising: (a) providing a ceil population comprising neural precursor cells, wherein the cell population is obtainable from embryoid bodies differentiated from human pluripotent stem cells; (b) differentiatin
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Lysine-specific Demethylase 1 (lsd1) Is a Biomarker for Breast Cancer
The present invention relates to novel biomarker for breast cancer, namely LSD1 and its application in inter alia the diagnosis of breast cancer. Furthermore, the present invention discloses a method of determining the LSD1 protein amount and the effect of LSD1 inhibitors on cancer cells selected fr
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Fully Crosslinked Chemically Structured Monolayers
The present invention relates to a structured monolayer, which is composed of low molecular weight aromatics and in the lateral direction of fully networked, with the mono-layer on one of the two surfaces of a pattern of functional groups, a method for producing such a structured monolayer and their
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Perforated Membranes
The present invention relates to a membrane with at least one molecular mono layer built up of low molecular aromatics and cross-linked in the lateral direction, wherein the membrane comprises a thickness in the range from 1 to 200 nm and a perforation in form of openings with a diameter in the rang
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Device, Instrument and Process for Detecting Magnetically Labeled Analytes
The present invention is directed to a device for quantitative analysis of an analyte in a liquid sample by detecting a magnetic label, an instrument for controlling the analysis process and displaying the results and a method for performing said analysis with said device and said instrument.
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Method for Measurement of the Force which Acts on an Object which Is Held in Optical Tweezers/an Optical Catch, and Optical Tweezers/an Optical Catch
The invention relates to a method for measurement of the force which acts on an object which is held in optical tweezers/an optical catch, in which the light which is scattered back from the held object through the objective of the optical tweezers/catch is detected by a detector and the detector si
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Layer system based on a high magnetic field or semiconductor-hybrids, comprises layers of a half-metallic ferromagnet, in an alternating arrangement, and a semiconducting compound, or a semiconducting
Layer system based on high magnetic field/semiconductor-hybrids, comprises one or more layers of a half-metallic ferromagnet, in an alternating arrangement, and a semiconducting compound, or a semiconducting non-stoichiometric compound. Layer system based on a high magnetic field/semiconductor-hybri
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CpG island sequencing
The present invention is directed to a method for analyzing the methylation status of a genomic DNA sample, comprising the steps of (i) fragmenting said sample and enriching said sample for sequences comprising CpG islands, (ii) generating a single stranded DNA library, (iii) subjecting said sample
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Graphite Layers
The present invention relates to a process for preparing graphite layers, comprising the step of heating at least one monolayer with low molecular weight aromatics and/or low molecular weight heteroaromatics crosslinked in the lateral direction under reduced pressure or inert gas to a temperature of
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Genes Encoding the Biosynthetic Pathway for Etnangien Production
The present invention provides the genes encoding the biosynthetic pathway enzymes and the biosynthetic pathway enzymes for producing in a host micro-organism the compound etnangien. The invention provides the coding sequences and the respective translation products obtainable therefrom, which const
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Reconfigurable Magnetic Logic-circuit Array and Methods for Producing and Operating Such Logic Devices
The invention relates to a reconfigurable magnetic logic-circuit array having at least two magnetoresistive elements, each composed of at least two magnetic layers, which are separated from one another by an intermediate layer, in each instance, whereby one of the magnetic layers, as a reference lay
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Method and Apparatus for Stabilizing a Laser Beam
The invention relates to a method for stabilizing a laser beam, in particular for stabilizing the profile intensity and/or the pendulum motion, in which an initial laser beam (1) is split into two partial beams (2, 3), wherein the two partial beams (2, 3) are rotated relative to one another by 180 d
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Method for Stabilizing a Laser Beam
The invention relates to a method for stabilizing a laser beam, which performs a reciprocating movement about a pivot point, at an examination location, in which the pivot point (D1) of the reciprocating movement is projected onto the examination location (D2) by means of an arrangement having at le
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One-step Method for Applying a Metal Layer Onto a Substrate
The invention relates to a one-step method for applying at least one metal layer onto a substrate by means of a gas phase deposition method. A substrate is coated with a metal layer in that a metal from a metal-containing precursor compound is precipitated from a gas phase onto the substrate, the me
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Joining coated materials using stamp rivets with semi-hollow rivets
Before the coated sheets are joined, a sacrificial plate (5) with a specially shaped cavity is placed on the matrix (3), to act as an underlay on which the materials to be joined (1) are laid. With the stamp rivet process, the sacrificial plate is shaped into the cavity in the matrix and after the s
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Nano-microphone Or Pressure Sensor
The invention relates to a method and a device for measuring or detecting and/or generating of pressures or pressure changes, in particular acoustic vibration and a method for production of such a device. The invention particularly relates to a nano-microphone. The device comprises at least one nano
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Self-propelled tilling device e.g. robot, navigating method, involves determining driving direction by evaluating determined vectors and by controlling distance to preceding tracks, and forming meande
The method involves capturing surrounding images e.g. 360 degree panorama image, in track points by a camera module (10). Vectors from actual track points to two preceding track points are determined by comparing the surrounding images of the actual track points with the surrounding images of the tw
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Production of a transparent aluminum oxide protective layer on a glass substrate for household glassware comprises feeding aluminum-containing precursor compounds into a coating chamber containing a g
Production of a transparent aluminum oxide protective layer on a glass substrate comprises placing a glass substrate in a coating chamber, feeding aluminum-containing precursor compounds in liquid or gas form into the chamber, converting the precursor compounds into the gas phase and depositing an a
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Method for Controlling an Auditory Game and Associated Device
The invention relates to a method for controlling an auditory game, wherein the displacement of a game element is given in a real time and is soundly reproducible. The inventive method consists in determining once the beginning event of movement in the state of motion of the game object in a three-d
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Device and Method for Measurement
Substances either separated or not by means of 1D or 2D flat bed electrophoresis or chromatography can be directly measured without pre-marking, by means of measuring the fluorescence thereof in the UV region with a UV detector, the above being stimulated by means of irradiation with UV light in the
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Differentiation of Human Embryonic and Induced Pluripotent Stem Cells
The invention relates to culture systems, methods, and conditions that allow pluripotent undifferentiated hESCs or iPSCs to progressively and uniformly differentiate into cells of the chondrogenic lineage.
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Oxidation of Environmental Contaminants with Mixed Valent Manganese Oxides
Methods and compositions for reduction of contaminants using manganese-based octahedral molecular sieves.
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Thin-Film Passive Samplers for Detection of Hydrophobic Organic Contaminants and Estrogenicity in Various Environments
A thin-film passive sampler for use in detecting hydrophobic organic contaminants in air or aqueous environments. The sampler features a relatively thin layer of a suitable absorbent matrix coated directly on a solid support unit made of an inert material such as titanium or glass fibers. The passiv
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Blends of Amorphous and Semicrystalline Polymers Having Shape Memory Properties
Blends of amorphous and semicrystalline polymers having shape memory properties were prepared by blending a crystalline polymer such as poly(vinylidene fluoride), polylactide, poly(hydroxxybutyrate), poly(ethylene glycol) polyethylene, polyethylene-co-vinyl acetate, poly(vinyl chloride), poly(vinyli
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Implantable Medical Devices
A medical device includes a balloon catheter having an expandable member, e.g., an inflatable balloon, at its distal end and a stent or other endoprosthesis. The stent is, for example, an apertured tubular member formed of a polymer and is assembled about the balloon. The stent has an initial diamet
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Pervaporation Composite Membrane for Aqueous Solution Separation and Methods for Using the Same
In one embodiment, a membrane comprises: a nonporous, hydrophobic selective layer configured to be on a feed solution side of the membrane and polyethylene layer configured to be on a permeate side of the membrane, wherein the membrane is configured to selectively separate an organic component from
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Depth and Lateral Size Control of Three-dimensional Images in Projection Integral Imaging
A method disclosed herein relates to displaying three-dimensional images. The method comprising, projecting integral images to a display device, and displaying three-dimensional images with the display device. Further disclosed herein is an apparatus for displaying orthoscopic 3-D images. The appara
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Methods of Inhibiting Vascular Permeability and Apoptosis
Agonists of vascular endothelial sphingosine-1-phosphate receptors are described. Compounds such as FTY720 can be phosphorylated by sphingosine kinase-2 into the phosphorylated forms which serve as sphingosine-1-phosphate receptor agonists. The vascular endothelial sphingosine-1-phosphate receptor a
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Electricity Generation in Single-Chamber Granular Activated Carbon Microbial Fuel Cells Treating Wastewater
An apparatus and method for producing electrical power and treating wastewater is provided. The apparatus and method oxidize bacteria and substrates naturally occurring in wastewater in a chamber, generating electrons which run from an anode to a cathode through an associated circuit. As a result of
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Coatings, Materials, Articles, and Methods of Making Thereof
A thermal spray process comprises injecting precursor solution droplets into the hot zone of the thermal spray flame. Also described are materials resulting from the process.
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Increased Activity of Catalyst Using Inorganic Acids
The present disclosure provides for improved electrochemical devices (e.g., fuel cells, metal air batteries, ultra capacitors, etc.) and components therefore. More particularly, the present disclosure provides for improved systems and methods for producing materials, membranes, electrode assemblies
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Systems for Alkyl Ester Production
In one embodiment, an alkyl ester production system can comprise: a first transesterification reactor comprising a liquid biomass inlet located between a liquid glycerol outlet and a liquid alkyl ester outlet, a water wash vessel comprising an alkyl ester inlet, a water inlet located near a top of t
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Shape Memory Main-chain Smectic-c Elastomers
Shape memory main-chain smectic-C elastomers are described, as are methods for their preparation and monomers used in such methods. The elastomers are prepared by hydrosilylation of a reaction mixture including a liquid crystalline diene, a crosslinking agent, and a bis(silyl hydride) compound. The
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Using Heat Shock Proteins to Improve the Therapeutic Benefit of a Non-vaccine Treatment Modality
The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an alpha-2-macroglobulin (alpha2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an alpha2M preparation is administer
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Methods for the Detection and Monitoring of Congestive Heart Failure
Disclosed herein are methods of detecting and/or prognosing congestive heart failure by detecting a proteolytic fragment of caspase-3 such as the p17 fragment or the p12 fragment. The congestive heart failure can be of any etiology, such as systolic or diastolic heart failure, ischemic or non-ischem
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Systems and Methods for Enhanced Control of Laser Drilling Processes
Systems and methods are provided for monitoring and/or controlling laser drilling processes based on atomic emission spectral emissions that are collected in real time during laser drilling. The systems and methods may be used to monitor and control laser drilling operations across a range of materi
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Compositions and Methods for the Inhibition of Hepatitis C Viral Replication with Structural Analogs
Compositions and methods for the inhibition of viral replication are provided. In some embodiments, the compositions include a nucleic acid sequence that is identical to a region of the hepatitis C virus (HCV) genome. In other embodiments, the compositions may include a nucleic acid sequence that ha
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Chemical Oxidization of Volatile Organic Compound
PROBLEM TO BE SOLVED: To effectively oxidize volatile organic compounds in the soil. ; SOLUTION: Volatile organic compounds are removed from the contaminated soil by introducing one or both of a water-soluble peroxygen compound, such as a persulfate, and a permanganate into the soil, either in situ
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Low-temperature Surface Doping/alloying/coating of Large Scale Semiconductor Nanowire Arrays
A method and corresponding system for providing a uniform nanowire array including uniform nanowires composed of at least three elements is presented. An embodiment of the method includes growing an array of two-element nanowires, and thereafter uniformly doping or alloying each two-element nanowire
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Biosensor for Continuous Monitoring of Metabolites and Proteins and Methods of Manufacture Thereof
A biosensor comprises a substrate; a reference electrode; a working electrode; a counter electrode; and a plurality of permeability adjusting spacers. The reference electrode, the working electrode and the plurality of permeability adjusting spacers are all being disposed to be substantially paralle
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Carbon nanotube composite scaffolds for bone tissue engineering
The present invention provides biocompatible composite materials that can be fabricated into a scaffold having properties suitable for bone repair and regeneration. These scaffolds have sufficient mechanical strength to be useful for the repair and regeneration of cortical bone.
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Resonant Leaky-Mode Photonic Elements and Methods for Spectral and Polarization Control
Optical devices with versatile spectral attributes are provided that are implemented with one or more modulated and homogeneous layers to realize leaky-mode resonance operation and corresponding versatile spectral-band design. The first and/or higher multiple evanescent diffraction orders are applie
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Compounds for Lysosomal Modulation and Methods of Use
Compounds useful for promoting lysosomal processes and thereby ameliorating the disruption of cellular and functional integrity induced by Ass and other protein and glycoconjugate species are provided. Methods for the treatment of neurodegenerative diseases that involve protein accumulation and aggr
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Detecting and Revoking Pirate Redistribution of Content
Disclosed are methods, systems and articles for tracing and disabling one or more unauthorized distributors of content originally transmitted by a distribution center. In some embodiments, a method includes receiving rebroadcast transmissions of a data segment previously transmitted by the distribut
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Nucleic Acid Materials for Nonradiative Energy Transfer and Methods of Production and Use
Nucleic acid materials for FRET-based luminescence and methods of making and using the nucleic acid materials are provided. The nucleic acid materials provide an innovative and synergistic combination of three disparate elements: a nucleic acid material, the processing technique for forming a nuclei
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Methods and Compositions for Inhibiting Atherosclerosis and Vascular Inflammation
Disclosed herein are compositions and methods for reducing inflammation associated with atherosclerosis and/or vascular inflammatory disease. The methods include administering to a subject in need of treatment for atherosclerosis and/or vascular inflammation a pharmaceutically effective amount of an
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Factor Viii Formulations
A Factor VIII (FVIII) composition formulated such that NaCl is not present in the final formulation or is present in trace amounts, which allows for a concomitant reduction in the lyophilization cycle time and increased stability of the lyophilized FVIII.
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Mechanically Competent Natural Polymer Based Porous Grafts for Bone Repair and Regeneration
The invention provides a scaffold for bone or cartilage replacement, in which the scaffold is fabricated from naturally derived polymers. In one embodiment the invention provides a bone replacement scaffold, wherein the scaffold comprises sintered polysaccharide microspheres. In a particular embodim
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Structural/biological Implant System
A structural/biological implant and method of use. The implant being utilized as a single or multiple staged system that is designed to encourage new alveolar bone growth with or without the need to obtain autologous bone. The implant has an apical portion that is fastened into existing bone, with t
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Glucose Sensors and Methods of Manufacture Thereof
Disclosed herein is a device that functions as a glucose sensor. The device has a reference electrode; a counter electrode, a working electrode; an electrically conducting membrane; an enzyme layer; a semi-permeable membrane; a first layer of a first hydrogel in operative communication with the work
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