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Sparkling Yogurt
Sparkling Yogurt® is a lightly carbonated yogurt with a unique, refreshing taste. The carbonation imparts a pleasant tingling sensation. In test marketing, customers purchased sparkling yogurt two times to one over regular yogurt.
General Information
Sparkling Yogurt® is lightly carbonated, spoo
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Sutureless Chest Drain Dressing
Background
Air or blood in the pleural cavity is a serious condition which can become life threatening. World-wide, it is estimated that 5 million chest drains are inserted annually. Currently, chest drains are secured in place using an arrangement of stitches, dressing pads and self-adhesive ta
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Mouse Models of Rhinovirus-induced disease
Background
Rhinoviruses cause the common cold, hospitalization of infants, pneumonia in the immunosuppressed and the majority of acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD). These diseases generate hundreds of billions of dollars in healthcare costs, and the morb
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Use of Equol for Treating Skin, Hair, Brain and Prostate Health and Obesity/Weight Control
General Information
Dihydrotestosterone (DHT) is a metabolite of the principal male hormone testosterone. However, it is more powerful than testosterone because of its increased affinity for the androgen receptor. DHT’s function is to promote male secondary sex characteristics, such as growth of
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Novel Sirtuin Activating Compounds
An improved method of synthesizing stilbene analogs, specifically resveratrol, that can activate sirtuins with increased efficiency, activity, and stability.
General Information
Sirtuins are NAD+ - dependent deacetylases that regulate many cellular processes that promote cell survival in respons
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Liquid-phase Reactor for Catalytic Production of Biomarkers from Biological Materials
Liquid-phase Reactor for Catalytic Production of Biomarkers from Biological Materials - A method for rapid identification of biological materials such as Anthrax.
General Information
In 2001, just a week after the terrorist attacks on the World Trade Center in New York City, high quality anthrax
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Method and Apparatus for Monitoring and Restoration of Shunt Function
General Information
Hydrocephalus is a condition where cerebrospinal fluid (CSF) in the brain accumulates in the ventricles and increases pressure within the skull. It is routinely treated through insertion of a catheter in the brain connected to a shunt that acts to redirect CSF to other areas o
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Portable Imperial College Surgical Assessment Device (pICSAD)
Background
Dexterity is a crucial aspect of surgical competence. Technical ability to perform a procedure is considered to be crucial for a safe and effective outcome and is also an important aspect of surgical training. However, a lack of haptic feedback particularly in laparascopic surgery t
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Automated Traffic Stopped Delay Data Acquisition
The traffic stopped delay algorithm rapidly determines the stopped delay of the traffic (which is the time each vehicle is stopped in the queue of a lighted intersection) from the video feed provided by intersection cameras. This information is traditionally gathered manually and used for operationa
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Direct Machining (DMAC)
Direct Machining (DMAC)-The process of driving production machines directly from a higher order part description such as CAD. DMAC integrates the part description software and machine controller on the same PC, eliminating numerous intermediate post-processing and control steps and much of the contr
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MousePuter
Imagine setting down your Smart Phone and PDA on the desk of a conference room, and connecting wireless to a flat panel TV on the wall. You connect a wireless keyboard to your PDA and begin to run a spreadsheet that is displayed on the 60” flat panel TV. Your Smart phone becomes a mouse to move arou
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Simple Authentication for the Web - SAW
A secure and convenient alternative to the numerous User IDs and passwords used for online accounts. Securely authenticates users through their email accounts to avoid difficulties in managing and remembering site specific User IDs and passwords.
Users can access an online account by simply input
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Icesheets
ICESHEETS is a brand new spreadsheet technology that combines the power of a large database with the ease of use of a spreadsheet. It gives a user the ability to view and access to multiple data sets in the same spreadsheet. Information such as monthly statements, financial reports, cost breakdowns,
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Water jet propulsion drive for boats
Marine water jet propulsion consist of a engine who drive a water (one or two) pump ,in this case a variable displacement pump (VDP) protected by a granted PATENT. The water are discharged backwards at high velocity trough nozzles in the transom and the thrust will be directed in forward direction.
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Oil Reservoir Simuluation
A new method has been developed to quickly determine fine-grid reservoir simulation pressures. It is estimated that the pressures in a one-billion cell simulation model can be determined in less than one percent of the time required by other state-of-the-art solvers. Increased accuracy is obtained b
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VoxelVision Software for 3D Object Segmentation
General Information
VoxelVision is imaging software that interactively segments and displays images of 3D anatomy derived from MRI, CT, or ultrasound scans. While other 3D imaging software is available, it is either too simplistic or takes too long to be of value. VoxelVision works with a few mou
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Glass Matrix to Preserve Proteins and Biopolymers
This glass-like matrix preserves proteins without refrigeration or freezing. Appropriately plasticizing carbohydrate or polymeric glasses yields a biopreservation matrix that can provide stability enhancement for encapsulated biological agent of as much as 100-fold over current best-practice formula
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Botulism Strain Detection
Real Time Polymerase Chain Reaction Quadraplexed for Rapid Detection of Clostridium botulinum Toxin Types A, B, E, and F
General Information
The toxin produced by Clostridium botulinum (botulism) is one of the most potent toxins known. It is believed that only one gram, properly aerosolized an
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Biomarkers for Predicting Preterm Birth
General Information
Preterm delivery is the number one complication of pregnancy affecting more than 10% of all pregnancies. It is the leading cause of illness and death associated with newborns. Compared with babies born at term, infants born prematurely have a 40-fold increase in neonatal death
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Active Sound Transmission Control of a Double-Panel Partition
An actively controlled, bidirectional partition that can provide excellent low-frequency attenuation while remaining relatively light weight. Significantly reduces low-frequency noise in systems like aircraft fuselage trim panels, rocket payload fairings, large ceilings, and high-rise buildings with
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Near-Field Active Noise Suppression
A multi-channel adaptive control algorithm with system hardware placed in the acoustic near-field for the active minimization of primarily tonal noise from axial flow fans.
General Information
The current invention consists of a design for an active control system that will significantly reduc
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Edge Reinforced Construction Sheeting
Edge-Reinforcement of Plywood & OSB – The Edge Reinforced Panel (ERP) was developed as a solution to the nail tear-out problem and consists of a reinforcing strip of fiber-glass or alternate strengthening and bonding material applied to the edge or nailing strip of a plywood or OSB sheet. The strip
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IsoTruss®
IsoTruss® grid structures offer a lightweight and efficient alternative to wood, steel, aluminum and traditional composite structures. The geometric grid shape in the fiber-reinforced composite structure is able to support tremendous axial tension, compression, torsion, or flexure loads.
General
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Cooking Utensil with Improved Heat Retention
A cooking utensil with improved heat retention includes an inner pot received within an outer pot and separated in a closely spaced-apart relationship to form a volume or chamber therebetween. The chamber is evacuated and sealed with foil leaves at the upper edges of the inner and outer pot. The vac
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Gas-Controlled Dynamic Vacuum Insulation with Gas Gate
Disclosed is a dynamic vacuum insulation comprising sidewalls enclosing an evacuated chamber and gas control means for releasing hydrogen gas into a chamber to increase gas molecule conduction of heat across the chamber and retrieving hydrogen gas from the chamber. The gas control means includes a m
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Enhanced Tunnel Junction for Improved Performance in Cascaded Solar Cells
BACKGROUND: Solar energy created through photovoltaics is finding increasing interest as an alternative power source for domestic and industrial use. The amount of power generated by a solar cell array is limited to the amount of solar cell area. In order to increase power delivery, the efficiency
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Process for Alkane-Group Dehydrogenation with Organometallic Catalysts
BACKGROUND: Saturated hydrocarbons are among the most abundant components of petrochemicals, but they are generally unreactive in chemical reactions. Alkenes and arenes, however, are more reactive and are very useful as raw materials in the organic chemical industries. Thus, there has been much inte
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Innovative catheters - for dilating difficult lesions and delivering therapeutics to the Diseased Artery Wall
New Market Opportunity: Therapeutic delivery
Advances in local drug delivery have proven extremely effective in the coronary arena. Drug-eluting stents have made a significant breakthrough in the prevention of instent restenosis. However, there are a number of areas where drugeluting stents cannot
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A Natural Biomaterial for Tissue Repair
New Market Opportunity
Any resection of the body wall for surgical correction of cancer, traumas or after radiotherapy requires reconstruction of the same wall with a prosthetic material to protect the critical structures, maintain the function with aesthetically acceptable results. At present thi
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Novel Orthopaedic Scaffolds for Spinal Implants
New Market Opportunity
Spine implants are the fastest growing segment in the $7-billion U.S. orthopaedic implants market. However, surgeons have long been awaiting a way to get more reliable results in spinal fusion surgeries. The rate of fusion failure in spine surgeries is 30% to 50%, so huge po
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Live-Cell based assay for DNA Damage Response
New Market Opportunity
Cell-based assays play a decisive role in the current drug screening process, yielding safer drugs in a cost effective manner. Such assays offer the potential to screen out compound failure earlier in the discovery and development lifecycle, delivering increased productivity
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Novel Targets for Preterm Labour
New Market Opportunity
Over 4 million births occur annually in the US, between 0.5-1 million women are treated annually with tocolytic drugs to halt early preterm labour contractions, while annual tocolytic drug sales of in the USA are estimated at up to $500 million. With over 8 million births in
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Shape-controlled Silver Nanoparticle Ink (“ArgentInkTM”)
New Market Opportunity:
Silver nanoparticle inks have applications in a wide number of fields across the electronics, physics, chemistry and biomedical fields. The optical absorption and fluorescence characteristics of the silver nanoparticles are critical to their functionality in all applications
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Fibre Hole Breakthrough Inspection System for Laser Micromachining (BreakThrough-Fibre)
New Technology Offering and Market Opportunity:
BreakThrough-Fibre is an innovative hole inspection technology which uses side-emitting fibre optic illumination and detection to improve the quality control of laser drilled holes in catheters and narrow-bore tubes. The system allows real-time detect
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A naturally occurring CXCL12gamma chemokine has potent anti-HIV-1 activity
FEATURES
The ability of chemokines to block HIV-1 infection has stimulated interest in the mechanism of their antiviral activity and potential use as therapeutic agents. Stromal cell-derived factor 1 (SDF-1)/CXCL12 is a member of the CXC chemokine family and has also been shown to block human immu
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Front-side Breakthrough Sensor for Laser Micromachining (BreatThrough-Vision)
New Technology Offering and Market Opportunity:
BreakThrough-Vision is an innovative machine vision and breakthrough sensor technology which improves the control and quality of the laser micromachining process. Laser micromachining finds applications in a wide number of fields across the mechanical
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High Resolution Phase Contrast Imaging of Phase Objects in the Human Eye for Glaucoma Diagnosis, Cellular and Microcirculation Imaging (“HR-PCI”)
New Market Opportunity
The human eye is a challenging and constrained optical system within which to perform optical imaging. One of the greatest challenges in applied optics has been to image, in vivo, using optical coherence tomography (OCT), certain transparent cells and the aqueous humour in t
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Novel High Volume Process for the Production of Silver Nanoparticles with Controlled Shape and Dimension (SilverFluidicsTM)
New Market Opportunity:
Silver nanoparticles have applications in a wide number of fields across the electronics, physics, chemistry and biomedical fields. The optical absorption and fluorescence characteristics of the silver nanoparticles are critical to their functionality in all applications. Th
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Aluminum-Based Metallic Glass Alloys
This novel metallic glass is nearly two times stronger than any previously existing aluminum alloy. This amorphous aluminum alloy is formed in thin flexible ribbons. By layering the ribbons with a polymer, sheets are produced that can be formed into any shape.
The alloy is extremely resistant to
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Directed Vapor Deposition of Electron-Beam Evaporant
We have developed a new electron-beam vapor deposition technology that combines traditional electron-beam evaporation with gas stream deposition techniques for high efficiency metal or reactive metal-oxides. Our system allows more rapid, more efficient deposition of multi-component coatings and film
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Smart Barrier for Spin Torque Transfer Random Access Memory (STTRAM)
As the scaling of traditional CMOS devices goes beyond the 32-nm node, the present memory technology will face numerous technical hurdles. MRAM is an emergent memory technology that has the potential to replace all other current memory technologies, including SRAM, DRAM and FLASH. Conventional MRAM
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In Plane Metal-Oxide-Oxide-Metal Diode Prepared by Selective Anodization
It is expected that the Moore’s law progression of CMOS technology will end in less than two decades, and there is a worldwide search for new devices that can either extend Moore’s law or provide a totally new pathway for information processing and communication. Using metals instead of semiconducto
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Multi-Functional Field Effect Switches Utilizing Anodized V/VO2/V Junctions
Vanadium oxides have a rich history because of the metal insulator transitions that several of the oxides and sub-oxides exhibit. In particular, VO2 has a metal–semiconductor transition just above room temperature in which this compound goes from a monoclinic crystal structure semiconductor below 34
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Closure Device for Skull Plates
An estimated 18,000+ people will develop brain tumors this year in the US, and over 30,000 people will develop subarachnoid hemorrhages caused by brain aneurysms. Aneurysms and brain tumors are only two of the several conditions that require neurosurgical procedures for treatment. Neurosurgical proc
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Epicardial Ablation Catheter and Access Sheath and Methods of Use
Today most electrophysiologic ablations are done from the endocardium because many superventricular tachycardias originate there. However, two of the fastest growing areas of ablation atrial fibrillation ablation and ventricular tachycardia (VT) ablation have significant contributors in the epicardi
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Epicardial-Cathode Catheter for Ablation Procedures
Two million Americans suffer from atrial fibrillation, which can cause palpitations, syncope, strokes and is associated with death. Cardiac ablations are becoming a standard method of treatment utilizing radiofrequency energy to render tissue, which is electrically faulty, inactive. However, AF abla
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Manometrically-Monitored Introducer Needle and Method of Use
Congestive Heart Failure (CHF) affects over 5,000,000 people in the U.S. alone and its incidence is growing. As the number of CHF cases grows, so will the rate of Ventricular Tachycardia (VT). Implantable Cardioverter Defibrillators (ICDs) can prevent sudden death from VT and drug therapies are ofte
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Method and Means for Intracranial Implantation of Carmustine Anti-Tumoral Agents
Biodegradable wafers containing the anti-tumoral agent carmustine (BCNU) are often inserted into the surgical void in the brain following the debulking of a glioma. The timed-release of the drug and subsequent diffusion of it into the peri-tumoral region allow for an effective, although relatively s
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Steerable Epicardial Lead to be Placed via the Subxiphoid
Congestive Heart Failure (CHF) is a significant and growing healthcare problem with almost five million patients suffering from this condition in the U.S. alone. The resulting hospitalization costs for treating these patients are $15B. While there have been numerous advances in treating CHF, few pat
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74.1, Vertebrate Cytoplasmic Dynein
This monoclonal antibody is for one of the polypeptides of vertebrate cytoplasmic dynein. This antibody is an IgG and is therefore more useful than IgM; it is also prepared with mammal (cow) antigen, not chicken. This clone is useful for western immunoblots, immunocytochemistry and immunoprecipitati
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Counter-Current Fluid-Fluid Flows Mixer (C2F3M)
The process of mixing fluids, or fluids and particulates, is critical in biology, chemistry, medicine, and engineering and in numerous applications involving the synthesis of pharmaceuticals, flows through biomedical devices, the fabrication of materials, the food industry, and contamination of the
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An On-Chip Signal Suppression Countermeasure to Power Analysis Attacks
Smartcards, cards where information is stored locally on an embedded integrated circuit rather than a magnetic strip, are examples of secure hardware devices that are becoming prolific in use. Such devices are used for everything ranging from toll payment and secure access identification cards to AT
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Ductile Bulk Amorphous Steel Alloys
Iron-based bulk metallic glasses (BMGs) are being studied as a potentially new types of structural materials because of their high strength, good corrosion and wear resistance coupled with relatively low materials cost. Among these Fe-based BMGs are the previously reported amorphous steels based on
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Fluorescent Boron Difluoride Diketone Polymers
Fluorescence technology is an integral part of new scientific assays and imaging methods in addition to its omnipresence in our everyday lives. The inventors have designed a novel polymer that coordinates boron difluoride with diketone ligands which results in a highly fluorescent compound. The appl
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Improved Method for Fabrication of Microfluidic Devices Allowing Functional Tuning
Miniaturization of analytical methods and instrumentation for clinical applications is an area of burgeoning interest. Microchips have been developed for many applications in order to minimize both the time and space required to perform processes such as drug delivery and clinical diagnostic procedu
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Super Rich Hydrogen Storage Nanomaterials with Intermediate Bond Strength
The quest for vehicles powered by alternative sources of fuel such as hydrogen has led to an explosion of research into new materials for storing and releasing hydrogen. Currently, one of the main challenges in the large scale development of hydrogen as a fuel is that a convenient and economical sto
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Monolithic Photodiode Array with Impedance Match
High-bit-rate optical fiber networks and photonic microwave applications currently rely on photodiodes to serve as optical-to-electrical (O/E) converters. In such high performance, high-speed applications the O/E converters must exhibit high 3db bandwidth as well as a large saturation photocurrent.
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AST - Atomic Simulation Tool
The University of Virginia has developed a user-friendly personal computer-based atomic scale simulation code for designing and evaluating ion beam deposition systems. This work entails first defining an ion gun-target-substrate geometry, material system(s), and a chamber background pressure, and th
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Low Power / high sensitivity CMOS circuits to be used to build Sensors
Solution / invention summary :
7 inventions all related to developing very low power CMOS integrated circuits. These inventions involve simple novel designs allowing the CMOS circuits to operate with very weak currents (in some cases with no current) in a nano-Ampere range or sub-nA range (1 nA or
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Process for Thermo Catalytic Cracking (TCC) of heavy oils feeds to increase production of light olefins (Ethylene-Propylene) at low Temperature
Solution / invention summary :
TCC Process is operated in existing steam cracking reactors and uses a novel catalyst material to increase the production of Ethylene-Propylene at a lower cracking temperature and with heavy hydrocarbon feed materials. TCC is very selective to light olefins. Catalyst
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New fiber reinforced plastic rod for the reinforcement of Concrete
Solution / invention summary :
New fiber reinforced plastic rod for the reinforcement of concrete. The rod has helical ribs and lobes along its length and has mechanical interlock built within. With this technology, the shear transfer between the rod and the concrete is through mechanical interlock
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A library containing more than 3000 new enzymes produced by 14 Fungi
Solution / invention summary :
14 fungi have been grown in various harsh conditions in order to produce a variety of enzymes. A high throughput platform is then used to isolate some 3000 new enzymes. A few of them are being tested by industrial partners.
Advantages / benefits :
The isolated enz
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Process for the development of epoxy nanocomposites
Solution / invention summary :
Recent development in nanocomposite technology using organoclay as nanoscale reinforcement offers an interesting alternative for modifying epoxy resins. The new patented process enhances the degree of exfoliation of the organoclay and breaks up the agglomerates. The n
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Planar waveguide grating device having Controlled Polarization Dependent Sensitivity and Method of Manufacturing thereof
Solution / invention summary :
Method of manufacturing that controls efficiently the effects of polarization dependent loss (PDL) and polarization dependent lambda (PDλ).
Advantages / benefits :
- The Echelle grating device is much smaller than other commercial technologies like the ones based
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Intelligent video surveillance
Solution / invention summary :
Object extraction and event analysis algorithm for video signal processing allowing the automation of video surveillance. - Open architecture / Linux;
- Real time processing;
- Software vs hardware;
- Generic definition of parameters;
- Identification and tracking
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Immunoassay biophotonic plateform
Solution / invention summary :
The invention combines a low density microfluidic biochip to a detection and amplification system that emits a fluorescent signal with antigenes/antibody proteomic reaction that is analysed through an Echelle type reflective micro-spectrometer.
Advantages / benefit
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Silica Nanoboxes
Microporous crystalline materials (e.g. zeolites, aluminophosphates), also called molecular sieves, are widely used as catalysts, adsorbents, and membranes. Two factors largely determine the utility of such materials: their regular nanoscaled size of pores and cavities, and their structural rigidity
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Synthesis of Colloidal Upconverting Monodisperse Nanocrystals for Biological Applications
Description of the technology: Synthesis, characterization, and spectroscopy of upconverting lanthanide-doped NaYF4 nanocrystals (NCs). Monodisperse cubic NaYF4 NCs were synthesized via a thermal decomposition reaction. Colloidally stable solutions of NaYF4 NCs in nonpolar organic solvents can be o
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Adventitial Delivery of Agents for the Treatment and Prevention of Restenosis
FEATURES Balloon angioplasty is one of the most widely used treatments for heart and vascular disease with an estimate of nearly two million procedures performed each year. However, roughly 25% of patients treated with balloon angioplasty experience renewed narrowing of the treated arteries, or rest
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Apoptosis-Inducing Compound for the Treatment of Cancer
FEATURES
Aside from surgery and radiation therapy, traditional chemotherapeutic treatment of cancer is commonly used even though it has detrimental side effects. Current chemotherapeutics are effective to treat cancer because they induce maturation (i.e. slowing growth) of the cells or they kill t
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Aryl and Vinyl Amination
FEATURES
The invention provides methodology for carbon-nitrogen bond formation via vinyl or aryl amination. An sp2 hybridized radical is reacted with an azomethine moiety to form pyrrolidine and indole compounds.
BENEFITS
The invention provides a facile process for the syntheis of compunds ha
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Automatic Retractable Floor System for 360 Degree Rotating Gantry
FEATURES
A commercial360 degree rotating gantry has a hazardous cavity for radiation technologists and nurses working in the area. Horizontal, pneumatically actuated, retractable floor plates aligned with the treatment room permanent floor are designed to cover this cavity and automatically retra
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Brachytherapy Catheter Positioning Guide
FEATURES
Stenosis of arteries or veins by the formation of atherosclerotic plaque is a well known and frequent medical problem. The most common procedure to treat such blockages is a technique commonly referred to as a "balloon angioplasty." In many patients the newly opened vessel undergoes reste
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Carrier for Medical Equipment for Motor Vehicle Transport
FEATURES
The inventor’s observational surveys of children with special health care needs have shown that families transport their needed equipment unrestrained. In the event of a motor vehicle crash these objects become projectiles. This invention is a light weight carrier designed to safely tran
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Control System for a Power Supply
FEATURES
Power supplies are used in numerous devices and applications as sources for voltage and/or current. In some devices, such as mass spectrometers, the accuracy of the voltage output of a power supply is a consideration in the overall performance of the device. Voltage drift and noise can ad
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De novo Peptide Sequencing Using a Covalent Derivatization Strategy
FEATURES
Research Tool. The invention describes a dual labeling strategy that enhances the mass spectrometry analysis of peptides. A de novo sequencing method is described that utilizes both guanidination of lysine residues in conjunction with amidination of the N-termini of peptides to be analyze
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Device for Controlled Placement of Effluents from Mechanically or Electrically Driven Separations
TECH FIELD(S)
Analytical Chemistry, Mass Spectrometry, Proteomics
FEATURES
The analysis of samples utilizing analytical chemistry techniques frequently requires the samples to be subjected to a number of successive techniques in order to obtain the desired information. This is particularly tru
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Device for Digital Retinal Imaging
FEATURES
A digital camera with simplified optics for imaging the retina and anterior structures.
BENEFITS
* The device can be produced at lower cost that current products. In addition, it will be easier to operate which will facilitate use in lesser developed regions of the world. Moreover,
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Get Connected
Software program that connects and configures first-time users to a campus network
TECH FIELD(S)
Software security for higher education networks
FEATURES
Get Connected eases the burden of initially linking thousands of students in university living residences to a campus network. Eve
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System and Method for Authenticating the Genuineness of Products Using Information Technology
The invention involves the use of sms, sms-capable telephone, database computer and sealed codes to authenticate the genuineness of physical products at the point of sale or anytime thereafter. The advantage of the system over prior art include the following:
a. It is extremely difficult to compro
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Diabetes
TECH FIELD(S)
Software and Information Technology
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FEATURES
Diabetes is a stereoscopic and standard video resolution computer generated animation of causes and effects of diabetes in humans to help educate middle school students. This three minute and f
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Disease Diagnosis by Profiling of Serum Glycans
TECH FIELD(S)
Medical-Biomarkers
FEATURES
A distinct goal in cancer diagnosis has been detecting cancer-related changes in patient's blood. Some recently identified cancer biomarkers in human serum are glycoproteins. However, this approach has been less commonly pursued due to the difficulties
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Disposable Two-Way Valve Filter for Use in Re-infusion After Blood Clot Removal
FEATURES
Several of the current treatments for thrombotic conditions such as arterial emboli and thrombosis, deep vein thrombosis and pulmonary thromboembolytic disease, require mechanical fragmentation of clots followed by aspiration of clot fragments. During removal, moderate to large amounts o
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DMP1 as a drug target for bone diseases
TECH FIELD(S)
Medical- Therapeutics
FEATURES
We have discovered and validated dentin matrix protein-1 (DMP-1) as a target for bone formation. Either agonists or antagonists could be engineered based on this target or fragments of the target protein to treat disorders by regulating bone minera
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DNA and Protein Library Construction Methodology
A method for building and polymerizing artificial coding sequence (6-mers) for the creation of unique nucleic acids and proteins from a limited number of amino acids
TECH FIELD(S)
Research Tool
FEATURES
A method for producing novel libraries with limited amino acid diversity that contain
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Doxcycline-inducible and brain-specific HIV-1 Tat transgenic mice
TECH FIELD(S)
Research Tool
FEATURES
Human immunodeficiency virus type 1 (HIV-1) Tat protein has been implicated in the pathogenesis of a number of AIDS-related disorders including HIV-induced neuropathogenesis. However, most of the studies demonstrating Tat neurotoxicity have been performed i
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Enediyne Compounds
TECH FIELD(S)
Medical-therapeutic
FEATURES
The potent antitumor activity of the enediyne natural product antibiotics such as calicheamicin, dynemicin, esperamicin, and neocarzinostatin has fostered interest in the development of simple enediynes with low thermal barriers to the formation of th
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Enhanced Palladium (Pd) catalyst for hydrogenation and oxidation reactions
Palladium nanoparticle and polymer matrix catalyst that exhibits high substrate conversion and stability
TECH FIELD(S)
Palladium metal catalyst invention
FEATURES
Pd catalysts are used in the hydrogenation and oxidation of many industrial products. For example, Linalool (LN), a fragrance
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Fluorescent in Situ PCR
TECH FIELD(S)
Research Tools-Diagnostics
FEATURES
In situ PCR (polymerase chain reaction) has become a powerful molecular tool in research as well as clinical practice. This technique has resulted in an increased understanding of infectious and neoplastic diseases and improvements in diagnosis
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Ginko biloba (EGb 761) protection against HIV-associated neurological diseases
TECH FIELD(S)
Medical-Therapeutic
FEATURES HIV-1
Tat protein is an important pathogenic factor in HIV-associated neuropathogenesis although there are few therapies that have been developed to specifically target HIV infection in the brain. Researchers at Indiana University have discovered that
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Glycan Markers of Hepatocellular Carcinoma
TECH FIELD(S)
Medical Biomarkers
FEATURES Hepatocellular Carcinoma (HCC) is a worldwide health problem. Serum alpha-fetoprotein, the current marker for HCC, is not effective for early diagnosis. It would be advantageous to develop markers for early detection of HCC. The inventors employed MALDI-
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Human Papillomavirus 6
TECH FIELD(S)
Research Tools
FEATURES
Human Papiilomarvius 6 gene sequence and expression construct.
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Improved Intravenous Catheter and Delivery System
FEATURES
A common problem faced by practitioners introducing intravenous (IV) catheters is the uncertainty as to whether the catheter is properly positioned within the vein. A major reason for this uncertainty is that the practitioner bases his judgment of proper insertion upon the observation of
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Intranasal Delivery System for Treating Central Nervous System Disorders
TECH FIELD(S)
Medical-Therapeutic
FEATURES
Central nervous system disorders have a significant impact on the quality of life of millions of people worldwide. Therapeutic treatment of these disorders has been difficult to achieve due to the absence of a sustained drug delivery system, as oral a
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Microfluidic device forming enhanced spatial and temporal gradients
Microfluidic device improving on current chemical gradient-generation designs in the forming of spatial and temporal gradients in a compact structure
TECH FIELD(S)
Microfluidic devices
FEATURES
Available is an improved microfluidic design for generating spatial and temporal chemical gradi
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Novel Antibacteria proteins
TECH FIELD(S)
Medical-therapeutic
FEATURES
Innate immunity is the first line of defense a body has against microorganisms. This innate immunity includes components of the immune system such as phagocytic and pro-inflammatory cells (neutrophils and macrophages) and humoral components (lysozyme,
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Novel Monomer-Free Light-Cured Glass-Ionomer System for Improved Dental Restoratives
FEATURES
Glass-ionomer cements are one of the most promising restoratives in dentistry. Since their invention, these cements have been successfully applied in dentistry for more than 25 years. The success of these cements is attributed to the facts that they are known for their unique properties s
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Novel Pharmocotherapeutic Process and Composition for Central Nervous System Disorders
TECH FIELD(S)
Medical-Therapeutic
FEATURES
An effective method of delivering neuroactive peptides to the brain and spinal cord that overcomes problems of poor absorption, rapid metabolism, poor blood brain barrier (BBB) penetration, and negative side effects has been pursued by scientists for
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Percutaneous Stent-Graft and Method for Delivery
FEATURES
Over 130,000 patients undergo chronic hemodialysis in the United States each year. The procedure requires access to the patient’s vascular system, but such access may eventually fail due to the formation of scar tissue inside the vessel or due to vessel occlusion. Failure of hemodialysi
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Percutaneous Thrombolytic Reinfusion Device
FEATURES
Blood clots, such as thrombi (localized clots) and emboli (clots which have moved through the bloodstream), can pose serious health risks, including stroke, breathing difficulty, other attendant health concerns and death. As such, a safe and effective method of removing such clots is high
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